2.Book Chapter (13)
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Item TRANSFORMING STUDENT ENGAGEMENT THROUGH AI, AR, VR, AND CHATBOTS IN EDUCATION (Book Chapter)(IGI Global, 2025-03-05) Viji Gripsy J; Selvakumari, Sheela N. A; Sheeba L; Senthil Kumaran BEmerging technologies have a relatively short history in the higher education sector. The term “AI-powered chatbots” refers to systems that use conversational AI. Many colleges and universities are taking advantage of conversational AI and deploying AI-powered chatbots to improve the student experience. It is possible to converse with a chatbot via text or voice using an AI-based interactive interface. Data is fed into chatbots, which are programmed to process information already given to them. They respond according to a pre-written script. By mimicking Alexa and Siri at home, conversational AI can help colleges and universities communicate with their students and prospective students in the same way. The primary aim of this chapter is to introduce the integration of Augmented Reality (AR) and Virtual Reality (VR) for AI-powered Chatbots for Transnational Higher Education to enhance the learning experience for students. The ultimate goal is to analyze the role of AI in improving higher education institutions around the globe.Item INTEGRATED MOLECULAR STRATEGIES FOR ENHANCED PRODUCTION OF ANTI-CANCER COMPOUNDS FROM ABUTILON HIRTUM (LAM.) SWEET (MALVACEAE) (Book Chapter)(CRC Press, 2025-01-01) Devi, Balasundaram Saraswathy Chithra; Tharani S; Elakkiya M.R; Krishnasreya M; Wesley, P. ServinAbutilon hirtum (Lam.) Sweet, a member of the Malvaceae family, has garnered attention for its rich reservoir of bioactive compounds, particularly those with potential anti-cancer properties. Various studies have explored the medicinal potential of Malvaceae plants, revealing a diverse array of bioactive compounds like alkaloids, cardiac glycosides, saponins, tannins, phenolic acids, and mucilages. Studies indicate that extracts or compounds derived from Abutilon hirtum exhibit promising effects against various cancer types. Several species within the Abutilon genus have also been recognized for their medicinal properties, with Abutilon hirtum being particularly rich in beneficial phytochemicals. To enhance the production of these secondary metabolites, a range of biotechnological methods are employed. Plant cell suspension culture and in vitro adventitious root culture are vital techniques used to boost secondary metabolite production. These methods have been successful in various plant species, generating compounds with pharmacological, nutraceutical, and industrial significance. Elicitation techniques, including the use of abiotic and biotic elicitors, are utilized to stimulate secondary metabolite production in suspension and adventitious root cultures, thereby increasing biomass and the concentration of pharmacologically active compounds during plant growth. Additionally, the use of nanomaterials as elicitors presents a promising avenue for augmenting secondary metabolite production and bolstering plant resilience to environmental stressors, with potential benefits for human health. Moreover, the review discusses recent advancements in biotechnological approaches, such as metabolic engineering and genetic modification, to further amplify the production of bioactive molecules from Abutilon hirtum. Overall, this synthesis provides insights into the potential of biotechnological interventions for optimizing the production of anti-cancer compounds from Abutilon hirtum, paving the way for future research and applications in cancer therapeutics.Item INTEGRATED MOLECULAR STRATEGIES FOR ENHANCED PRODUCTION OF MEDICINAL PLANT-DERIVED ALKALOIDS (Book Chapter)(CRC Press, 2025-01-01) Devi, Balasundaram Saraswathy Chithra; Krishnasreya M; Tharani S.; Elakkiya M.RMedicinal plants continue to be an important source of life-saving drugs for humankind. The secondary metabolites responsible for plant defense mechanisms through cytotoxic activity toward microbial pathogens have proved to be useful as antimicrobial medicines in humans. One such group of secondary metabolites is alkaloids; they are nitrogenous organic heterocyclic molecules that have pharmacological effects on humans and other animals. They are used as antihypertensives, sedatives, antitumor agents, anticholinergic drugs, anesthetics, psychoactive, analgesics, antispasmodics, and antibacterials, and are also used in treating neurodegenerative disorders and mood disorders. In plants, alkaloids are present only in small quantities. This chapter reviews the molecular strategies that can be employed to increase alkaloid production from medicinal plants.Item MUTAGENESIS FOR ENHANCED SECONDARY METABOLITES PRODUCTION IN MEDICINAL PLANTS (Book Chapter)(CRC Press, 2025-01-01) Tharani S; Mutharaian V.N; Thirugnanasampandan R; Moin, Sarmad; Devi, Balasundaram Saraswathy ChithraMedicinal plants have long been recognized as valuable sources of secondary metabolites with diverse pharmacological and therapeutic properties. The controlled manipulation of plant genomes through mutagenesis offers a promising avenue to enhance the production of these bioactive compounds. This abstract discusses the principles and applications of mutagenesis techniques, including chemical and radiation-based methods, as tools to induce genetic variations in medicinal plants. It also explores the subsequent identification and selection of high-yielding mutants, along with their stable propagation and evaluation under controlled and field conditions. Induced mutations have been successfully employed to develop enhanced versions of several therapeutic plants. This approach has the potential to substantially increase the yield of secondary metabolites, thereby addressing the growing need for these compounds. Additionally, it contributes to the sustainable cultivation of medicinal plants, reducing pressure on wild populations. However, it is vital to consider ethical, environmental, and regulatory aspects when employing these techniques to achieve the desired enhancement of secondary metabolites. The application of mutagenesis in enhancing secondary metabolite production offers a pathway to harness the full potential of medicinal plants for their therapeutic and economic value.Item CURCUMIN-LOADED NANOPARTICLES IN NEURODEGENERATIVE DISEASES: ALZHEIMER’S, PARKINSON’S, AND AMYOTROPHIC LATERAL SCLEROSIS (Book Chapter)(Springer Science and Business Media B.V., 2025-02-21) Palanisamy, Senthilkumar; Balasubramanian, Aiyar; Kanchana, Marimuthu; Sisubalan, Natarajan; Selvakesavan, Rajendran KNeurodegenerative diseases, including Alzheimer’s disease (AD)Alzheimer’s disease (AD), Parkinson’s disease (PD)Parkinson’s disease (PD), and amyotrophic lateral sclerosis (ALS), are characterized by progressive neuronal loss and have limited treatment options. CurcuminCurcumin, a bioactive compound derived from turmeric, exhibits multiple neuroprotective properties, making it a potential therapeuticTherapeutics agent for these conditions. However, its clinical use is restricted by poor bioavailability and rapid metabolism. CurcuminCurcumin has shown promise in treating neurodegenerative diseases like AD, PD, and ALS due to its anti-inflammatory, antioxidant, and neuroprotective properties. However, its clinical application is hampered by poor solubility in aqueous solutions, rapid metabolism, and limited bioavailability. These challenges have led researchers to explore innovative strategies to enhance curcuminCurcumin’s therapeutic potential. One promising approach is the use of nanoparticle-based delivery systems, which address these limitations by improving curcuminCurcumin’s stability and permeability across the blood-brain barrier (BBB)Blood-brain barrier (BBB) and providing controlled drug release. NanoparticlesNanoparticles (NPs) offer a viable solution to the challenges associated with curcuminCurcumin delivery. Their unique physicochemical properties, such as enhanced stability and targeted delivery capabilities, help overcome hurdles posed by curcuminCurcumin’s rapid metabolism and poor solubility. For instance, curcumin-loaded nanoparticles (CLNPs) have demonstrated improved drug bioavailability and better brainBrain penetration. Studies have shown that these nanoparticles enhance the therapeutic effects of curcuminCurcumin in neurodegenerative diseases by ensuring sustained release and targeted delivery, thereby addressing key limitations of curcuminCurcumin’s clinical use. Despite their potential benefits, several challenges remain in the application of CLNPs. Achieving consistent and efficient delivery across the BBBBlood-brain barrier (BBB) is a significant obstacle that must be addressed. Additionally, while CLNPs can enhance curcuminCurcumin’s bioavailability, the long-term safetySafety and efficacy of these formulations require further investigation. Potential concerns include immune responses, toxicityToxicity, and the scalability of manufacturing processes. Addressing these challenges through continued research and development will be crucial for the successful clinical translation of CLNPs, ensuring their safetySafety and effectiveness in treating neurodegenerative diseases. This chapter explores the innovative use of nanoparticle-based delivery systems to enhance the therapeutic potential of curcuminCurcumin in treating AD, PD, and ALS.Item DIGITAL TWINS & INDUSTRY 5.0 ON FOOD MANAGEMENT (Book Chapter)(Springer, 2025-02-23) Sanfiya S; Sabitha Banu ADigital twins have the potential to transform agri food production systems and supply chains, addressing critical challenges such as greenhouse gas emissions, food waste, and malnutrition1. These virtual representations of physical entities exist in silicon, continuously updating based on real-time sensor data. By simulating physical systems, digital twins can optimize behaviour and advise control strategies for their physical counterparts. For instance, they can help estimate and predict food quality, enabling stakeholders to make dynamic decisions about supply chain logistics and storage conditions to reduce spoilage and wastage. Additionally, digital twins support end-to-end visibility and traceability, enhancing supply chain management by overseeing complex moving parts and building nonlinear supply chain models. The function of digital twins (DT) in the context of industry 5.0 is thoroughly explored in academics. Industry 5.0’s digital twin models minimize operational hazards, increase productivity for human users, and lessen wear and tear on real-world equipment. This study attempts to investigate the effects of the use of virtual twins. The way businesses conduct business is changing as a result of the rapid rise in the adoption of digital twin technology. In the past few years, digital twins have been extensively used in many important commercial applications, and it is expected that the equipment will expand to other businesses, scenarios of use, and applications. The purpose of this study is to evaluate the literature and look into how Industry 5.0 and Digital Twins can make intelligent automation easier in a variety of industries.Item CARBON-BASED NANOPARTICLES FOR NEURAL REGENERATION (Book Chapter)(Springer Science and Business Media B.V., 2025-02-21) Maghimaa M; Bharath S; Kandasamy, SabariswaranCarbon-based nanoparticles, particularly carbon nanotubes (CNTs), have demonstrated significant potential in neural regeneration due to their exceptional properties. Their high electrical conductivity and mechanical strength mimic the natural characteristics of neural tissues, supporting neuronal growth and function. Additionally, CNTs exhibit high biocompatibilityBiocompatibility, ensuring minimal toxicityToxicity and making them suitable for use in implantable neural interfaces. A key factor in their effectiveness is the ability to functionalize CNTs through chemical modifications. These modifications enhance their interaction with biological systems, improving neuronal attachment and facilitating the delivery of therapeuticTherapeutics agents. This targeted delivery provides essential growth factors and medications directly to damaged areas, promoting more effective nerve regeneration. Research indicates that CNTs contribute significantly to peripheral nerve regenerationRegeneration. They are utilized to create composite scaffolds that support axonal growth and aid in the repair of damaged neural tissues. When integrated into polymeric matrices, CNTs enhance cell adhesion and neurite outgrowth, both of which are crucial for neuronal recovery. Future research is expected to further advance the use of CNTs in neural regeneration. Innovations in functionalization techniques and broader clinical applications hold the potential to make effective treatments for nerve damage and degenerative diseases increasingly attainable. In summary, CNTs represent a powerful and versatile tool in neural regeneration, offering promising solutions for repairing nerve damage.Item THE FRINGE BENEFIT OF INDUSTRY 4.0 AND INDUSTRY 5.0 ON THE EDUCATIONAL SECTOR: A COMPREHENSIVE BIBLIOMETRIC REVIEW (Book Chapter)(IGI Global, 2025-01-31) Vijay, Vihas; Lakshmi, J. DivyaThis chapter presents a bibliometric analysis of literature published between 2012 and 2024, exploring the impact of Industry 4.0 and Industry 5.0 technologies on education. Using a dataset of 3281 Scopus-indexed records, the study identifies trends, research patterns, key contributions, and popular keywords. Bibliometric tools like Biblioshiny reveal global research trends, significant studies, and collaboration networks. The analysis highlights the influence of artificial intelligence, the Internet of Things, and robotics on education, particularly during the COVID-19 pandemic, emphasizing scenario-based learning and strategic human resource management. By examining the top 10 contributing papers, this study provides insights for policymakers, educators, and researchers, stressing the need for multidisciplinary research, global collaboration, and longitudinal studies to harness the educational potential of these technological advancements.Item THE TRIAD OF ORGANIZATIONAL SUSTAINABLE SUCCESS: EMOTIONAL INTELLIGENCE, TACIT KNOWLEDGE SHARING, AND PSYCHOLOGICAL SAFETY USING STRUCTURAL EQUATION MODELLING (Book Chapter)(Springer Science and Business Media Deutschland GmbH, 2025) Priyadharshini, S L; Ranchana, K; Savitha, S; Shanthini, B; Excelce, A JThe purpose of this study is to clarify the collective influence of psychological safety (PS), tacit knowledge sharing, and emotional intelligence (EI) on long-term success in organizational settings. Data was gathered from 311 employees employed in high-tech knowledge-intensive firms based in India and underwent analysis utilizing structural equation modelling alongside bootstrapping techniques. The results of our study indicate that emotional intelligence plays a notable role in bolstering tacit knowledge-sharing behaviors among employees, with psychological safety serving as a partial mediator in the correlation between emotional intelligence and tacit knowledge-sharing. These findings highlight how crucial it is to develop emotional intelligence skills and encourage the sharing of tacit knowledge.Item HARMONIZING POLICY OBJECTIVES WITH ECONOMIC DEVELOPMENT AND INDUSTRIALIZATION STRATEGIES (Book Chapter)(Springer Science and Business Media Deutschland GmbH, 2025) Mohanraj, S; Aiswarya Lakshmi, T; Nathiya, T; Yasodha Devi, L; Sujaritha, D; Gowrishankar, RThe objective of this qualitative study is to shed light on potential pathways for smooth integration at the regional or national levels by exploring the complex interactions that exist between policy goals and more general economic development methods. This study uses a novel technique called word cloud analysis to clarify the underlying thematic priorities and values that are ingrained in the policies that are now in place. Through close examination of the textual corpus of relevant policy papers, important themes surface that made clear the guiding principles and general objectives of governmental activities. This research identifies similarities and differences between policy goals and more general agenda for economic development through methodical examination. Word frequencies and co-occurrences are compared to provide a more detailed picture of the policy landscape, highlighting possible conflicts as well as areas of agreement. This approach facilitates the discovery of focal points for integration and synergy, directing policymakers toward the unification of divergent goals for comprehensive economic growth. Additionally, this study aims to close the knowledge gap between policymakers and practitioners by providing practical insights. Strategic recommendations are made to help ensure that policy objectives are smoothly incorporated into more comprehensive plans for economic development and industrialization. These recommendations are developed by combining the results of the word cloud analysis with qualitative evaluations. To promote synergy and coherence across several policy domains, these ideas include targeted interventions, stakeholder engagement initiatives, and institutional reforms. In the end, this study advances the conversation about successful policy integration for long-term, sustainable economic growth. It provides policymakers with a road map for navigating the challenges of policy convergence and promoting inclusive and cohesive economic growth at both the regional and national levels by utilizing cutting-edge methodology and qualitative insights.