3.Review (03)

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ADVANCES IN FIELD EFFECT TRANSISTOR BASED ELECTRONIC DEVICES INTEGRATED WITH CMOS TECHNOLOGY FOR BIOSENSING (Review)
(Elsevier B.V., 2025) Rai, Harshita; Singh, Kshitij RB; Natarajan, Arunadevi; Pandey, Shyam S
This review article embarks on an enlightening journey through the multifaceted realm of electronic devices and their applications in biosensing, emphasizing the role of Field effect transistor (FET) based biosensors and Complementary Metal Oxide Semiconductor (CMOS) processes in biosensing device development. It begins by elucidating the foundational principles of biosensing and underscoring the crucial contribution of transducers, establishing a robust understanding of the field. The article unravels the intricate interplay between electronic biosensors and CMOS processes, offering a concise yet insightful exploration of their operational intricacies, diverse practical applications, and recent advancements. Additionally, it spotlights the pivotal role of FET-based biosensors integrated with CMOS processes in miniaturizing biosensors and thus amplifying their real-world efficacy. Moreover, the role of modern technologies, such as the Internet of Things (IoT), in recent biosensor development has been discussed. By addressing inherent challenges like sensitivity, integration, cost, and accessibility, the article underscores the vital role of biosensing technologies driven by electronic devices in wearable technology development. In addition, integrating these devices to fit with the ongoing trend of VLSI technology faces significant challenges. To overcome this aspect, sensors based on molecularly imprinted polymers (MIPs) can be the best alternative, as they will avoid utilizing bioreceptors, as it simplifies integration by reducing complexity, enhancing stability, and improving compatibility with CMOS processes. Hence, this review's distinct contribution lies in its comprehensive approach, shedding light on how biosensing technologies, underpinned by electronic devices such as FETs and CMOS processes, offer solutions for realizing modern-day devices.
RECENT TRENDS IN USE OF PLANT-DERIVED CARBON DOT-BASED FLUORESCENT PROBES FOR HEAVY METAL ION DETECTION AND THEIR BIOLOGICAL APPLICATIONS (Review)
(Elsevier B.V., 2025) Venkatesan, Geetha; Sathiyan, Govindasamy
Plant-derived carbon dots (CDs) have drawn a lot of interest as superior nanomaterials because of their sustainable nature, biocompatibility, and environmentally friendly synthesis, which sets them apart from other CDs made from non-renewable resources. The synthesis of CDs from natural sources such as fruits, leaves, bark, stem, flower, seed and biowaste by hydrothermal, pyrolysis, and microwave-assisted method have been investigated to modify the size and features of CDs. The plant-derived CDs exhibit greater sensitivity and selectivity, and their high photoluminescent properties makes it possible to detect physiological and ecological significant metal ions like iron (Fe³⁺), copper (Cu²⁺), lead (Pb²⁺), and mercury (Hg²⁺). This study focuses mainly on crucial elements such as absorption, emission, sensitivity, selectivity, and limits of detection of metal ions, a thorough examination of their sensing characteristics is provided. This review article comprehensively summarizes plant-based CDs with different synthesis methods, characterization techniques, metal ion sensing and its mechanism, stability and biological imaging of CDs. Additionally, we discussed the plant derived CDs for the detection of pesticides and drugs. These CDs also find extensive applications in environmental remediation by offering a sustainable alternative for detecting harmful pollutants. Beyond these sensing, their biological uses of plant-derived CDs, such as bioimaging, antioxidant activity, and therapeutic potential, are finally addressed. This review emphasizes the bright future of plant-derived CDs in biomedicine and sustainable nanotechnology, with a focus on their biological applications and improved sensing capabilities in research development
NANOPLASTICS IN HEAT-SENSITIVE FOOD PACKAGING: A REVIEW OF MIGRATION, DETECTION, HEALTH, AND ENVIRONMENTAL IMPACTS (Review)
(Elsevier Ltd, 2025-03) Palanisamy, Senthilkumar; Saravana Kumar, Barani Kumar; Vetrivel, Aishwarya; Michael, Rahul Jacob; Babu, Nivethitha; Nallamuthu, Sanjay Sharan; Saravanan, Kokila; Venkatachalam, Shanmugam; Naveen Kumar, R J; Selvaraju, Gayathri Devi; Selvakesavan Rajendran, K; Lee, Jintae
The widespread use of plastics in food packaging, particularly during heat processing, has raised significant concerns about the release of micro- and nanoplastics into food. This review comprehensively examines the sources, detection methods, health impacts, and environmental consequences of micro- and nanoplastics generated from heat-packed food. The mechanisms by which these particles are released during heating, sophisticated analytical methods for their detection, potential health risks from consumption, and the effects of these particles have on the environment are covered in detail. Current regulatory frameworks and mitigation strategies are critically assessed, highlighting challenges and opportunities in managing plastic contamination. Key research areas are identified to address knowledge gaps and improve food packaging safety. This review informs decision-making and policy development to mitigate the risks associated with micro- and nanoplastics in heat-packaged food.