International Journals
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Item PHYTOCHEMICAL SCREENING FOR ACTIVE COMPOUNDS IN GLORIOSASUPERBA LEAVES AND TUBERS(International Journal of Pharmacognosy and Phytochemical Research, 2012-03) H, Rehanabanu; N, NagarajanGloriosasuperba Linn. (Family: Liliaceae) is one of the endangered species among the medicinal plants which is a striking tuberous climbing plant with brilliant wavy-edged yellow and red flowers common in forest throughout India and in Andaman Islands. The objective of this study was to evaluate the phytoconstituents of Gloriosasuperba leaf and tuber extracts. All experiments were conducted following standard procedures. The results revealed the presence of various classes of compounds such as alkaloids, flavonoids, saponins, glycosides, steroids, phenols and tannins. Resins was not detected from any of the extract under study. The results of the various phytochemical tests indicated that the plant to be rich in various biologically active compounds which could serve as potential source of the crude drugs that can be used as a complementary source of traditional medicines. We recommend further research on this plant for possible isolation and characterization of the various chemical active substances.Item POTENTIAL INHIBITORY EFFECTS OF GLORIOSASUPERBA ON HUMAN PATHOGENIC FUNGI(Pharma Science Monitor, 2012-07) H, Rehanabanu; N, NagarajanThe different solvent extracts viz., acetone, dichloromethane, chloroform and methanol extracts of GloriosasuperbaL. (Liliaceae) were screened for antifungal activity, by disc diffusion method against human pathogenic yeast and mould. The test organisms included were Candida albicansand Aspergillusflavus. The methanol extract of tubers recorded high significant antifungal activity against all the tested fungi. The least activity was found in the chloroform extractsItem ANTIBACTERIAL POTENTIAL OF GLORY LILY, GLORIOSASUPERBA, LINN(International Research Journal of Pharmacy, 2011-03) H, Rehanabanu; N, NagarajanThe successive Soxhlet extract of Gloriosasuperba, L. (Liliaceae) was extracted using acetone, dichloromethane, chloroform and methanol in ascending order of the polarity. The extracts were investigated for their antibacterial activity against two Gram positive bacteria Streptococcus faecalisand Enterococcus faecalisand two Gram negative bacteria Klebsiellapneumoniaeand Proteus mirabilis by using disc diffusion method. Among the four extracts tested, acetone extract had effective antibacterial potential, followed by methanol extract at 25 and 100% concentration against Enterococcus faecalis. The acetone extract showed greater activity against Gram-positive than against Gram-negative organisms. The study confirms the antibacterial potential of Gloriosasuperbaleaves extracted using various solvents, and is therefore, a potential drug that requires further studies and development