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    OCCURRENCE OF SOUTH AMERICAN SUCKER ARMOURED CATFISH (PTERYGOPLICHTHYS PARDALIS) IN THE GAYATHRIPUZHA RIVER, PALAKKAD, KERALA
    (International Journal of Fisheries and Aquatic Studies, 2023) Veena, V; Sasikala, G; Selvaraju, Raja
    An intensive survey was undertaken and reported the existence of an invasive armoured sailfin catfish Pterygoplichthys pardalis from the Bharathapuzha River, Palakkad, Kerala, India, and its invasion as one of the foremost threats to the endemic aquatic biodiversity of Kerala. It belongs to the Genus Pterygoplichthys (Siluriformes: Loricariidae) which is known as popular aquarium fish that constitutes one of the most successful aquatic freshwaters invasive taxa, having achieved global distribution. The invasion occurred through aquarium fish culture and trading and is intensified by the distribution through rainstorm flooding and irrigation canal. The fish were identified based on morphological tests, identified fishes ranged in length (9.50-31.75cm) and weight (8.16-129.80 g). Distribution leads to understanding the changes and disturbances in fish species composition and the negative impact on the riverine ecosystem.
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    ESTIMATING CHLOROPHYLL-A, CONCENTRATION USING SENTINEL-2 IMAGERY IN SELECTED LAKES OF KANYAKUMARI DISTRICT, TAMIL NADU, INDIA
    (EM International, 2021) C, Rojamadhuvanthi; N R, Chrips; P B, Harathi
    Water resources in India are very unpredictably distributed both spatially and temporally. Over the years, increasing population, urbanization and extension in agriculture and domestic water utilization has stressed the circumstances. Excessive algal growth due to eutrophication can have adverse effects on drinking water suppliers and end users. Monitoring of chlorophyll levels is the way to estimate the algal growth in water. Chlorophyll-a is one of the ecological indicators which is used to evaluate the status of the water bodies and its quality. Estimation of Chl-a had been carried out using in-situ data from Sentinel-2 imagery. For the present study, two lakes in Nagercoil districts - Parakkai Lake (P1, P2, and P3) and Therekal Lake (P4) were selected for the estimation of Chl-a using Sentinel-2 satellite imagery. Values of Chl-a concentration were estimated between 0.91-7.62 g/L for P1, whereas the values of P2 0.98-5.59 g/L and P3 the values range between 0.93- 5.43 g/L and Therekal lake (P4) is 0.97-7.01 g/L. Use of recent techniques like remote sensing and GIS (Geographical Information System) is still limited. Though the conventional methods give accurate values of Chl-a, but these results are not very helpful in providing a complete status of the whole water body. Estimation of Chl-a in water using the remote sensing techniques in integration with GIS which is associated with conventional methods.
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    PH DEPENDENT DRUG RELEASE OF SILIBININ, A POLYPHENOL CONJUGATED WITH MAGNETIC NANOPARTICLE AGAINST THE HUMAN COLON CANCER CELL
    (SpringerLink, 2020-04-03) Sennimalai, Ramya; Saranya, Thiruvenkataswamy; Krishnamoorthy, Kavithaa; Sivashanmugam, Preethi; Harysh, Winster; Vellingiri, Balachander; Manickam, Paulpandi; Arul, Narayanasamy
    Magnetic nanocarriers has become popularised in the research field as well as in the biomedical application due to their unique exotic possession, and processability. The present study involves the synthesis of nanocarrier, Iron Oxide nanoparticle conjugated with silibinin (SLN-Fe2O3) using co-precipitation method and also to detect their efficacy against the colon cancer cell. The synthesized SLN-Fe2O3 were undertaken for several analysis including UV-visible spectroscopy, dynamic light scattering, scanning electron microscope, Fourier transform infra-red spectroscopy, zeta potential analysis, and X-ray diffraction analysis. The analysis had end up in confirming the polydispersity and crystalline nature of the synthesized SLN-Fe2O3 with an average size of 70 nm. Further the synthesized SLN-Fe2O3 was undertaken for in vitro (AO/EtBR and DAPI) studies to find their effectiveness against human colon cancer using HT-29 cell line. The fragmentation occurs in nuclear material of the SLN-Fe2O3 treated cells had revealed that the cell death was due to the induction of apoptotic signals in the treated cancer cells. Thus the current study had clearly validated the potency of synthesized Iron Oxide nanoparticles conjugated with silibinin (SLN-Fe2O3) against the colon cancer cell and holds a promising therapeutic potency in treating cancer cells.
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    LARVICIDAL ACTIVITY OF DIFFERENT SOLVENT EXTRACTS OF NERIUM OLEANDER (APOCYNACEAE) RED COLOURED FLOWERS AGAINST AEDES AEGYPTI, ANOPHELES STEPHENSI AND CULEX QUINQUEFASCIATUS (DIPTERA: CULICIDAE)
    (2022-03-05) Pandeeswari M; Raja, Selvaraju; Yamuna R; Manu Thomas, Mathai
    Larvicidal activity of various solvent extracts of Nerium oleander red colored flower was studied against third instar larvae of three important vector mosquitoes viz., Aedes aegypti, Anopheles stephensi and Culex quinquefasciatus. Preliminary phytochemical analysis was done to all the solvent extracts showed the presence of Tannins, saponins, flavonoids, quinones, terpenes, phenols and coumarines are present in the red colour flowers extracts. Among the solvent extracts acetone extract was most effective when compared to other extracts. Cx. quinquefasciatus was the most susceptible (LC50=20.4 mg/L) and An. stephensi was the most tolerant (LC50=34.0 mg/L). Also, the extract was subjected to GC-MS analysis and 16 major biochemicals were detected. The present study clearly indicated that bioactive molecules present in the acetone extract of red color flower of N. oleander are promising botanical pesticide against vector mosquitoes.
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    RANDOM FOREST ALGORITHMS IN HEALTH CARE SECTORS: A REVIEW OF APPLICATIONS
    (Eureka Journals, 2021) Haripriya G; Abinaya K; Aarthi N; Praveen Kumar P
    Safety culture is a multidimensional phrase in healthcare delivery systems that have been linked to medical errors and patient safety incidents. Despite this, there is little evidence to suggest that safety culture characteristics have an impact on overall patient safety. Aside from that, complex statistical analysis has only been applied sparingly in previous data studies on safety culture practices. In healthcare, there is a centralized organization delivery systems is a multifaceted issue that is linked to medical errors and patient safety concerns. Using health facility aggregate data from the United States, this study investigates the communication between recognized organizational safety components and patient security grade to address these safety concerns. Random forests computer vision program based on trees technique, researchers use to predict accurate and stable relationships between variables. Amidst this, there is little information available about which aspects of patient safety culture are most important. Furthermore, advanced statistical analysis in previous reviews of data on safety culture has been limited, as previously mentioned. Additionally, random forests, a machine learning technique based on trees, estimate precise and stable associations between variables. As a result, researchers used data from a study in collective US hospitals to investigate the relationship between identified safety culture components and patient safety grades. As a result of the findings, the scientists found that healthcare quality knowledge, organizational factors, and top management objectives all play a crucial influence in determining patient safety grades. Security concerns in the work unit, as well as the work environment created by hospital management, have an impact on patient safety outcomes
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    PRELIMINARY STUDIES ON ANTIOXIDANT ACTIVITY OF EXTRACT OBTAINED FROM BLACK CARTENTER ANT CAMPONOTUS COMPRESSES (FAB.,) (HYMENOPTERA: FORMICIDAE)
    (INTERNATIONAL JOURNAL OF INNOVATIVE RESEARCH IN TECHNOLOGY, 2020-07) Yamuna, Ramakrishanan; Raja, Selvaraju
    Different types of toxins, debris and reactive oxygen species, commonly known as free radicals, are generated during metabolism by natural cell death, infections, pollution etc. The side effects of many drugs and medicines are also due to generation and accumulation of such free radicals. They cause many histopathological and physiological disorders leading to degenerative diseases. Thus, these wastes are to be disposed off and removed as early as possible for normal functioning of the body and healing process. In modern medical science it is believed that antioxidants, also known as free radical scavenging agents play an important role. Exogenous intake of antioxidants helps the body to scavenge free radicals effectively and to promote natural functioning of all body systems. In this present study, In vitro antioxidant activity of C. compressus extract was determined using DPPH radical scavenging method. A concentration dependent inhibition of DPPH radicals was observed with maximum activity (89.24 ± 0.005) at 4 mg/ml dose followed by other concentration tested, 3 mg/ml (79.24%), 2 mg/ml (65.48%) and 1 mg/ml (54.13%). At still higher concentration, 5 mg/ml (89.11%), a rather lower, and statistically at similarity, inhibition was noticed than the preceding concentration. The antioxidant activity of C. compressus may be due to the presence of bioactive peptides. Further detailed studies on the antioxidant activity of C. compressus extract observation on animals are needed to define the mechanism of antioxidant activity.