International Journals
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Item OCCURRENCE OF SOUTH AMERICAN SUCKER ARMOURED CATFISH (PTERYGOPLICHTHYS PARDALIS) IN THE GAYATHRIPUZHA RIVER, PALAKKAD, KERALA(International Journal of Fisheries and Aquatic Studies, 2023) Veena, V; Sasikala, G; Selvaraju, RajaAn intensive survey was undertaken and reported the existence of an invasive armoured sailfin catfish Pterygoplichthys pardalis from the Bharathapuzha River, Palakkad, Kerala, India, and its invasion as one of the foremost threats to the endemic aquatic biodiversity of Kerala. It belongs to the Genus Pterygoplichthys (Siluriformes: Loricariidae) which is known as popular aquarium fish that constitutes one of the most successful aquatic freshwaters invasive taxa, having achieved global distribution. The invasion occurred through aquarium fish culture and trading and is intensified by the distribution through rainstorm flooding and irrigation canal. The fish were identified based on morphological tests, identified fishes ranged in length (9.50-31.75cm) and weight (8.16-129.80 g). Distribution leads to understanding the changes and disturbances in fish species composition and the negative impact on the riverine ecosystem.Item CORRIGENDUM TO ‘VOLTAGE-GATED CALCIUM CHANNEL BLOCKERS DEREGULATE MACROAUTOPHAGYIN CARDIOMYOCYTES’ [INTERNATIONAL JOURNAL OF BIOCHEMISTRY AND CELL BIOLOGY(Elsevier, 2016-01) Charumathi, Pushparaj; Arindam, Das; Rosa, Purroy; Mireia, Nàger; Judit, Herreros; Reinald, Pamplona; Carles, CantíItem ESTIMATING CHLOROPHYLL-A, CONCENTRATION USING SENTINEL-2 IMAGERY IN SELECTED LAKES OF KANYAKUMARI DISTRICT, TAMIL NADU, INDIA(EM International, 2021) C, Rojamadhuvanthi; N R, Chrips; P B, HarathiWater resources in India are very unpredictably distributed both spatially and temporally. Over the years, increasing population, urbanization and extension in agriculture and domestic water utilization has stressed the circumstances. Excessive algal growth due to eutrophication can have adverse effects on drinking water suppliers and end users. Monitoring of chlorophyll levels is the way to estimate the algal growth in water. Chlorophyll-a is one of the ecological indicators which is used to evaluate the status of the water bodies and its quality. Estimation of Chl-a had been carried out using in-situ data from Sentinel-2 imagery. For the present study, two lakes in Nagercoil districts - Parakkai Lake (P1, P2, and P3) and Therekal Lake (P4) were selected for the estimation of Chl-a using Sentinel-2 satellite imagery. Values of Chl-a concentration were estimated between 0.91-7.62 g/L for P1, whereas the values of P2 0.98-5.59 g/L and P3 the values range between 0.93- 5.43 g/L and Therekal lake (P4) is 0.97-7.01 g/L. Use of recent techniques like remote sensing and GIS (Geographical Information System) is still limited. Though the conventional methods give accurate values of Chl-a, but these results are not very helpful in providing a complete status of the whole water body. Estimation of Chl-a in water using the remote sensing techniques in integration with GIS which is associated with conventional methods.Item PH DEPENDENT DRUG RELEASE OF SILIBININ, A POLYPHENOL CONJUGATED WITH MAGNETIC NANOPARTICLE AGAINST THE HUMAN COLON CANCER CELL(SpringerLink, 2020-04-03) Sennimalai, Ramya; Saranya, Thiruvenkataswamy; Krishnamoorthy, Kavithaa; Sivashanmugam, Preethi; Harysh, Winster; Vellingiri, Balachander; Manickam, Paulpandi; Arul, NarayanasamyMagnetic nanocarriers has become popularised in the research field as well as in the biomedical application due to their unique exotic possession, and processability. The present study involves the synthesis of nanocarrier, Iron Oxide nanoparticle conjugated with silibinin (SLN-Fe2O3) using co-precipitation method and also to detect their efficacy against the colon cancer cell. The synthesized SLN-Fe2O3 were undertaken for several analysis including UV-visible spectroscopy, dynamic light scattering, scanning electron microscope, Fourier transform infra-red spectroscopy, zeta potential analysis, and X-ray diffraction analysis. The analysis had end up in confirming the polydispersity and crystalline nature of the synthesized SLN-Fe2O3 with an average size of 70 nm. Further the synthesized SLN-Fe2O3 was undertaken for in vitro (AO/EtBR and DAPI) studies to find their effectiveness against human colon cancer using HT-29 cell line. The fragmentation occurs in nuclear material of the SLN-Fe2O3 treated cells had revealed that the cell death was due to the induction of apoptotic signals in the treated cancer cells. Thus the current study had clearly validated the potency of synthesized Iron Oxide nanoparticles conjugated with silibinin (SLN-Fe2O3) against the colon cancer cell and holds a promising therapeutic potency in treating cancer cells.Item LARVICIDAL ACTIVITY OF DIFFERENT SOLVENT EXTRACTS OF NERIUM OLEANDER (APOCYNACEAE) RED COLOURED FLOWERS AGAINST AEDES AEGYPTI, ANOPHELES STEPHENSI AND CULEX QUINQUEFASCIATUS (DIPTERA: CULICIDAE)(2022-03-05) Pandeeswari M; Raja, Selvaraju; Yamuna R; Manu Thomas, MathaiLarvicidal activity of various solvent extracts of Nerium oleander red colored flower was studied against third instar larvae of three important vector mosquitoes viz., Aedes aegypti, Anopheles stephensi and Culex quinquefasciatus. Preliminary phytochemical analysis was done to all the solvent extracts showed the presence of Tannins, saponins, flavonoids, quinones, terpenes, phenols and coumarines are present in the red colour flowers extracts. Among the solvent extracts acetone extract was most effective when compared to other extracts. Cx. quinquefasciatus was the most susceptible (LC50=20.4 mg/L) and An. stephensi was the most tolerant (LC50=34.0 mg/L). Also, the extract was subjected to GC-MS analysis and 16 major biochemicals were detected. The present study clearly indicated that bioactive molecules present in the acetone extract of red color flower of N. oleander are promising botanical pesticide against vector mosquitoes.Item STUDIES ON THE EFFECT OF SIDA ACUTA AND VETIVERIA ZIZANIOIDES AGAINST THE MALARIAL VECTOR, ANOPHELES STEPHENSI AND MALARIAL PARASITE, PLASMODIUM BERGHEI(Rishan Publications, 2014-03-26) Narasimhan, Aarthi; G, James Pitchai; Kadarkarai, Murugan; Pari, Madhiyazhagan; Thiyagarajan, Nataraj; Arjunan, Nareshkumar; Kandasamy, Kalimuthu; Jiang-Shiou, Hwang; Donald R, Barnard; Hui, Wei; R, Chandrasekar; A, AmsathThe methanolic extracts of Sida acuta and Vetiveria zizanioides leaves and root was investigated for antimalarial activity against Plasmodium berghei infections in mice. The median lethal dose was determined to ascertain the safety of the extract in mice. The antimalarial activities during early and established infections were evaluated. Phytochemical screening was also investigated to elucidate the possible mechanism of the antimalarial and antivectorial properties. The extracts of Sida acuta and Vetiveria zizanioides leaf and root demonstrated that a significant antiplasmodial activity in all the three groups (test for root and leaves and one control includes three groups) of the antimalarial evaluations. Plant extracts treatment showed higher mortality against mosquito larvae, lethal dose (Lc50 and Lc90) was also worked out for the larval instars of malarial vector, Anopheles stephensi. Phytochemical screening revealed that the presence of some vital insecticidal and antiplasmodial constituents such as terpenoids, flavonoids and alkaloids. The leaf and root extract of S. acuta and V. zizanioides showed markedly significant antimalarial activity and antivectorial activity effects even at low concentrations. O S. acuta and V. zizanioides are promising in mosquito control and also safe for the non-target organisms. This integrated application could be useful as alternative synthetic insecticides. These agents should preferentially to be applied in mosquito control strategies to reduce the mosquito populations and prevent the malaria.Item RANDOM FOREST ALGORITHMS IN HEALTH CARE SECTORS: A REVIEW OF APPLICATIONS(Eureka Journals, 2021) Haripriya G; Abinaya K; Aarthi N; Praveen Kumar PSafety culture is a multidimensional phrase in healthcare delivery systems that have been linked to medical errors and patient safety incidents. Despite this, there is little evidence to suggest that safety culture characteristics have an impact on overall patient safety. Aside from that, complex statistical analysis has only been applied sparingly in previous data studies on safety culture practices. In healthcare, there is a centralized organization delivery systems is a multifaceted issue that is linked to medical errors and patient safety concerns. Using health facility aggregate data from the United States, this study investigates the communication between recognized organizational safety components and patient security grade to address these safety concerns. Random forests computer vision program based on trees technique, researchers use to predict accurate and stable relationships between variables. Amidst this, there is little information available about which aspects of patient safety culture are most important. Furthermore, advanced statistical analysis in previous reviews of data on safety culture has been limited, as previously mentioned. Additionally, random forests, a machine learning technique based on trees, estimate precise and stable associations between variables. As a result, researchers used data from a study in collective US hospitals to investigate the relationship between identified safety culture components and patient safety grades. As a result of the findings, the scientists found that healthcare quality knowledge, organizational factors, and top management objectives all play a crucial influence in determining patient safety grades. Security concerns in the work unit, as well as the work environment created by hospital management, have an impact on patient safety outcomesItem PRELIMINARY STUDIES ON ANTIOXIDANT ACTIVITY OF EXTRACT OBTAINED FROM BLACK CARTENTER ANT CAMPONOTUS COMPRESSES (FAB.,) (HYMENOPTERA: FORMICIDAE)(INTERNATIONAL JOURNAL OF INNOVATIVE RESEARCH IN TECHNOLOGY, 2020-07) Yamuna, Ramakrishanan; Raja, SelvarajuDifferent types of toxins, debris and reactive oxygen species, commonly known as free radicals, are generated during metabolism by natural cell death, infections, pollution etc. The side effects of many drugs and medicines are also due to generation and accumulation of such free radicals. They cause many histopathological and physiological disorders leading to degenerative diseases. Thus, these wastes are to be disposed off and removed as early as possible for normal functioning of the body and healing process. In modern medical science it is believed that antioxidants, also known as free radical scavenging agents play an important role. Exogenous intake of antioxidants helps the body to scavenge free radicals effectively and to promote natural functioning of all body systems. In this present study, In vitro antioxidant activity of C. compressus extract was determined using DPPH radical scavenging method. A concentration dependent inhibition of DPPH radicals was observed with maximum activity (89.24 ± 0.005) at 4 mg/ml dose followed by other concentration tested, 3 mg/ml (79.24%), 2 mg/ml (65.48%) and 1 mg/ml (54.13%). At still higher concentration, 5 mg/ml (89.11%), a rather lower, and statistically at similarity, inhibition was noticed than the preceding concentration. The antioxidant activity of C. compressus may be due to the presence of bioactive peptides. Further detailed studies on the antioxidant activity of C. compressus extract observation on animals are needed to define the mechanism of antioxidant activity.Item EVALUATION OF LARVICIDAL ACTION OF NATURAL EXTRACTS ON MOSQUITO LARVAE OF AEDES AEGYPTI (DIPTERA: CULICIDAE)(Innovative Journal Solutions, 2016) Susheela P; Radha R; PadmapriyangaMosquitoes are known to cause more diseases than any other group of arthropods and affect millions of people throughout the world. The current study was aimed to investigate larvicidal potential of three natural extracts such as aloe vera and onion, alcohol and cloves, marigold and garlic against the dengue vector, Aedes aegypti. Insecticidal susceptibility tests were carried out using WHO standard method and the mortality was observed after 24-h exposure. All the tested extracts showed moderate to good larvicidal activities. However, the maximum larval mortality was observed in the extract of the alcohol and cloves that showed high efficacy on the Aedes mosquito larva. The findings of the present studies suggested that the use of aloe vera, onion and garlic has a strong effect in acting as a mosquito larvicide and the natural plant extracts can be prepared at home and used at any cost of time which is feasible for the massesItem STUDIES ON THE LIFE HISTORY AND OVIPOSITIONAL PREFERENCE OF CALLOSOBRUCHUS MACULATUS REARED ON DIFFERENT PULSES(International Science Community Association, 2014) Radha R; Susheela PThe pulse beetle, Callosobruchus maculatus (F.) (Coleoptera: Bruchidae), is a worldwide insect pest that infests pulses in the fields and seeds in storage. An investigation has been conducted on the life history and ovipositional preference of Callosobruchus maculatus reared on five different pulses. The oviposition period had not varied significantly between the pulses. The adults exhibited a marked preference for smooth, well-filled seeds for oviposition.The order of preference for Callosobruchus maculatus for oviposition were: Vigna unguiculata (cowpea) > Vigna radiata (green gram) > Vigna mungo (black gram) > Dolichos biflorus (horse gram) > Pisum sativum(green peas). The pulses selected for the investigation were initially infested by the insect, but the degree of infestation varied among the pulses. This is due to the varied responses of the insect to different host seeds for oviposition and their appropriateness for the successful completion of the life cycle.