a) 2024-Scopus Open Access (pdf)

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CONTROLLABILITY OF IMPULSIVE DAMPED FRACTIONAL ORDER SYSTEMS INVOLVING STATE DEPENDENT DELAY (Article)
(Universal Wiser Publisher, 2024) Arthi, G; Vaanmathi, M
In this article, the concept of controllability on fractional order impulsive systems involving state dependent delay and damping behavior is analysed by utilizing Caputo fractional derivative. The main motivation is to derive the sufficient conditions for the controllability of the considered systems. Based on the Laplace transform and inverse Laplace transform, the solution of fractional-order dynamical systems are obtained. The results are established by utilizing basic ideas of fractional calculus, Mittag-Leffler function and Banach fixed point theorem. Finally, an application is provided to illustrate the derived result.
CONTROLLABILITY OF STOCHASTIC FRACTIONAL SYSTEMS INVOLVING STATE-DEPENDENT DELAY AND IMPULSIVE EFFECTS (Article)
(Springer Science and Business Media Deutschland GmbH, 2024) Arthi, G; Vaanmathi, M; Ma, Yong-Ki
In this paper, the controllability concept of a nonlinear fractional stochastic system involving state-dependent delay and impulsive effects is addressed by employing Caputo derivatives and Mittag-Leffler (ML) functions. Based on stochastic analysis theory, novel sufficient conditions are derived for the considered nonlinear system by utilizing Krasnoselkii’s fixed point theorem. Correspondingly, the applicability of the derived theoretical results is indicated by an example
ENHANCED ENERGY EFFICIENT ROUTING PROTOCOL FOR ON DEMAND DISTANCE VECTOR ROUTING TO IMPROVE COMMUNICATION IN BORDER AREA MILITARY COMMUNICATION (Article)
(Prof.Dr. İskender AKKURT, 2024-10-02) Sangeetha, M; Parvathy, S; Deiwakumari, K; Veena, T; Badrinarayan, D
Soldiers get rescue services through static wireless node heliports and medical ambulance to provide special service, in a battle field. The Mobile Ad hoc Network environment takes wireless communication across border communication to connects the source of multiple serves in military applications. The mobile node acts as mobile equipment to rescue the soldier. Due to increasing delay tolerance and latency overhead the performance eon network is degraded, to resolve this problem , this paper concentrates on Region and Mobility based Route Request Processing in AODV (RMRRP) is proposed in controlling Route Request Processing mechanism based on node mobility for reducing the routing overhead in AODV. The routing algorithm which guarantees services to the soldier in a shortest time also evaluate the energy efficiency of RMRRP with the existing AODV, DSDV, DSR routing algorithms. Efficiently reduce the overall overhead to a considerable level and significantly improve the overall performance by finding a rectangular region as a forwarding zone and only the nodes within the rectangular region are allowed to forward the RREQ message from source to the destination, hence the overhead in establishment of a stable shortest path gets reduced very much. Network region is minimized. Routing request packets generated is less and route request is reduced. Region width is limited to 150m and within that covered area only route discovery and route maintenance is carried out. Control packets are reduced within the limited rectangular region and data packets are able to send more. Avoiding link breaks to send and receive more data packets with a limited number of control packets hence consumes considerable energy. Simulation result reveals that with nodes 50 the Packet delivery Fraction is 90.60 , Routing overhead is 11376, Normalized Routing Load is 3.61 , Throughput is 261.94Kbps, MAC Load is 39.17 , Energy consumption is 4.64 Joules.
ENHANCEMENT OF ELECTRICAL AND RADIATION SHIELDING PROPERTIES OF VANADIUM DOPED LITHIUM TELLURO-BORATE (LTB) GLASSES (Article)
(Elsevier B.V., 2024-06) Karthika, S; Sundari S, Shanmuga; Marimuthu, K; Meena, P
Vanadium doped lithium telluro-borate (LTB) glasses of the composition (20-x Li2O-20TeO2-60B2O3-( )V2O5 (x = 0, 0.5, 1, 1.5 and 2 in mol %) were synthesised by melt quenching technique. The structural, optical, physical, electrical and radiation shielding parameters of the prepared glasses were investigated to determine the effect of vanadium in the LTB glass matrix. Density of LTB glasses were found to increases from 2.52 to 2.98 g/cm3 under addition of vanadium oxide and certain density derived structural parameters were studied. XRD pattern confirms the amorphous nature of the pristine and doped LTB glass. FTIR spectra shows the presence of various bonds in the vanadium doped LTB glasses. The direct optical bandgap (Eg) decreases due to the addition of V2O5 and leads to creation of defects in the LTB glasses thereby increasing the Urbach energy (Eu). Physical parameters like refractive index (n), molar refractivity (Rm), reflection loss (Lr), molar electronic polarizability (αm), transmission coefficient (T) and metallization criteria (M) were calculated. The electrical properties including dielectric constant (εʹ), conductivity (σ) and activation energies (Ea) were analysed and observed that Ea decreases under the addition of vanadium to the glass network proving the enhancement in electrical conductivity. Radiation shielding parameters such as MAC, LAC, HVL, TVL, MFP, R, ACS, ECS, Neff, Zeff, and Ceff were calculated using Phy-X/PSD and LTB_2V with the highest V2O5 additive shows enhanced result in gamma radiation shielding.
EXOSOMES FOR SKIN TREATMENT: THERAPEUTIC AND COSMETIC APPLICATIONS - Review
(KeAi Publishing Communications Ltd., 2024-12) Sreeraj, Harsha; AnuKiruthika, R; Tamilselvi, K.S; Subha, D
The therapeutic potential of exosomes, which are nano-sized extracellular vesicles derived from various cell types, have drawn substantial interest in the field of dermatology. Exosomes have distinctive capabilities, including facilitating intercellular communication, delivering bioactive molecules, and modulating immune responses, which make them promising candidates for skin regeneration, wound healing, and treating dermatological disorders. Specifically, exosomes derived from the stem cells of mesenchymal and adipose cells, have numerous applications in skin repair and regeneration. Exosomes also find expanded applications in treatments and therapies related to hair. Exosomes emit signals and growth factors that impact the activity of nearby epithelial cells, encouraging their growth, specialization, and the development of hair formations. This review explores the efficacy of topical and transdermal applications of exosomes in skin and hair and highlight the transformative potential of exosome-based therapies in dermatology and pave the way for future research and clinical applications
NECESSARY OR SUFFICIENT CONDITION FOR ALEXANDROFF TOPOLOGICAL SPACES TO BE CORDIAL GRAPHIC (Article)
(Elsevier B.V, 2024) Divya, A; Ramya, K; Sasikala, D
In this paper, we explore the property of being a cordial graphic and establish that it corresponds to an Alexandroff topological space. We analyze how the characteristics of cordial graphs align with the principles of Alexandroff topology and provide insights into their topological structure.
A NEW HYBRID ADAPTIVE OPTIMIZATION ALGORITHM BASED WAVELET NEURAL NETWORK FOR SEVERITY LEVEL PREDICTION FOR LUNG CANCER DATASET (Article)
(Intelligent Network and Systems Society, 2024) Divya, T; Gripsy J, Viji
This study proposes three contributions focused on lung cancer detection and severity level identification. The absence of non-invasive technologies for predicting lung cancer necessitates faster, more efficient, and more accurate classification procedures due to the absence of non-invasive technologies for predicting lung cancer. Creating an automated and intelligent prediction system is crucial for identifying phases and predicting the possibility of a recurrence. The objective is to create an automated detection system for identifying lung cancer using an optimizationfocused deep learning model. We develop an adaptive multi-swarm PSO and combine it with the firefly algorithm to determine the ideal weight values for the Wavelet Neural Network (WNN) model. We use the HAPSO-FFA WNN method to explore problems with multiple optimal solutions. This study evaluated two lung cancer datasets, and the proposed HAPSO-FFA-WNN model achieved 97.58% accuracy for dataset 1 and 98.54% accuracy for dataset 2. Furthermore, the proposed model achieved better precision, recall, and MCC performance metrics.
OPTIMIZED ENERGY EFFICIENT- HIERARCHICAL CLUSTERING BASED ROUTING (OEE-HCR) FOR WIRELESS SENSOR NETWORK (WSN) (Article)
(European Alliance for Innovation, 2024) Reena G, Sophia; Nithya, S
The study into Wireless Sensor Network (WSN) has grown more crucial as a result of the many Internet of Things (IoT) applications. Energy – Harvesting (EH) technology can extend the lifespan of WSN; however, because the nodes would be difficult to get to during energy harvesting, an energy-efficient routing protocol should be developed. The use of clustering in this study balances energy consumption across all Sensor Node (SN) and reduces traffic and overhead throughout the data transmission phases of WSN. Cluster Head (CH) selection step of the Optimized Energy Efficient-Hierarchical Clustering Based Routing (OEE-HCR) technique involves sending data to the closest CH. In order to analyse and transmit each cluster data, CH will need to use more energy, which will hasten and asymmetrically deplete the network. Whale Optimization Algorithm (WOA) algorithm is introduced for the best number of clusters formation with dynamically selecting the CH. Experimentation analysis, results are measured using First Node Dead (FND), the Half Node Dead (HND), Last Node Dead (LND), and Maximum Lifetime Coverage (MLC) at the time of number of data transmission rounds performed in routing algorithms.
PHYTOCHEMICAL PROFILING OF ETHANOLIC EXTRACT OF BEE POLLEN USING GAS CHROMATOGRAPHY MASS SPECTROSCOPY AND ITS IN SILICO ANALYSIS OF HYPOCHOLESTEROLEMIC ACTIVITY (Article)
(Association for Advancement of Entomology, 2024-03) Ashwathi, K; Nandhini, V M; Thirumalai, V; Ezhili, N; Pushparaj, Charumathi
Bee pollen, a bee product, is considered as one of the valuable products in natural medicine, for its excellent therapeutic properties. Cold maceration technique was employed to extract bee pollen and the phytochemical constituents were analysed. The preliminary phytochemical analysis showed the presence of acids, proteins, carbohydrates, phenol, flavonoids, glycosides, anthraquinone, quinone, resins, saponin, tannin, and terpenoids. The advanced phytochemical screening of volatile chemical constituents analyzed using Gas Chromatography and Mass Spectrometry (GC-MS) showed 40 volatile chemical compounds from the bee pollen extract. Among those, the hypocholesterolemic effect-related compound of bee pollen was analyzed by in silico docking method, where Oxidosqualene:Ianosterolcyclase (OSC) was taken as a target enzyme which helps in cholesterol biosynthesis. Hexadecanoic acid, Pentadecanoic acid, Pyrroloindole, and Alpha amyrin selected as ligands, and Ro 48-8071 fumarate used as a standard enzyme inhibitor for molecular docking analysis, showed that all the ligands efficiently bound with the target enzyme OSC. Among the four compounds, alpha amyrin had the highest binding interaction energy with the target enzyme (-13.37 kJ mole-1). The OSC enzyme inhibition activity may be responsible for the hypocholesterolemic effect and weight-reducing property of bee pollen.
ROLE OF CHAPERONES AND ENDOPLASMIC RETICULUM STRESS IN PROTEIN COMPLEXITY ASSOCIATED WITH DYSLIPIDEMIA: A FUTURE PERSPECTIVE TO NOVEL THERAPEUTICS (REVIEW)
(Spandidos Publications, 2024-01) Al Huq Mohammed, Suhaib; Rajamani, Kiruba
Protein structure is extraordinarily complex and consists of various folding processes, namely, primary, secondary, tertiary and quaternary. Currently, researchers are eager to acquire knowledge and elucidate the mechanisms involved in these processes. Over the past decade, several studies have indicated that the endoplasmic reticulum stress (ERS) response assists in the protein response via intracellular signaling. ERS plays a key role in protein folding and unfolding. An increase in ERS promotes the unwinding of the folded protein. The present review specifically discusses the protein complexity involved in dyslipidemia (the condition of elevated cholesterol levels in the blood) with the ERS response and unfolded protein response. ERS in dyslipidemia is achieved by several pathological conditions, including oxidative stress, calcium imbalance and high levels of cholesterol in the blood. Therefore, in the present review, the ERS response in dyslipidemia is specifically highlighted as regards protein complexity, which indicates that considering oxidative stress, calcium imbalance and high levels of cholesterol would be a great benefit to reducing the ERS. The present literature review was performed using the search engines of the web‑based databases (Google Scholar and ScienceDirect) with keywords such as ‘Role of chaperones in dyslipidemia’ and ‘Protein complexity’ or ‘Protein involved in dyslipidemia’. Furthermore, the role of chaperones associated with ER in finding novel therapeutics for disease prevention is also discussed.
SINGLE MOLECULE REAL-TIME SEQUENCING DATA SETS OF HYPERICUM PERFORATUM L. PLANTLETS AND CELL SUSPENSION CULTURES (Data Paper)
(Nature Research, 2024-12) Selvakesavan, K Rajendran; Nuc, Maria; Kolarčik, Vladislav; Krajewski, Paweł; Franklin, Gregory
Hypericum is a large genus that includes more than 500 species of pharmacological, ecological and conservation value. Although latest advances in sequencing technologies were extremely exploited for generating and assembling genomes of many living organisms, annotated whole genome sequence data is not publicly available for any of the Hypericum species so far. Bioavailability of secondary metabolites varies for different tissues and the data derived from different cultures will be a valuable tool for comparative studies. Here, we report the single molecule real-time sequencing (SMRT) data sets of Hypericum perforatum L. plantlets and cell suspension cultures for the first time. Sequencing data from cell suspension cultures yielded more than 33,000 high-quality transcripts from 20 Gb of raw data, while more than 55,000 high-quality transcripts were obtained from 35 Gb of raw data from plantlets. This dataset is a valuable tool for comparative transcriptomic analysis and will help to understand the unknown biosynthetic pathways of high medicinal value in the Hypericum genus.
TAXONOMIC NOTES ON TWO ENDEMIC SPECIES OF OBERONIA LINDL. FROM WESTERN GHATS, INDIA (Article)
(Horizon e-Publishing Group, 2024-01) Kiruthika, K; Sulaiman, M; Murugan, C
The genus Oberonia is known for its micro floral arrangement. Due to its minute structure, excess of new species are reported. The present paper reveals the synonymization of two recently described species of the genus Oberonia viz. O. saintberchmansii and O. wynadensis under O. anamalayana and O. josephi respectively. The original illustration and live dissected images of the species are provided for easy identification.
Β-CHITIN AND CHITOSAN FROM WASTE SHELLS OF EDIBLE MOLLUSKS AS A FUNCTIONAL INGREDIENT (Article)
(John Wiley and Sons Inc, 2024-01) Karthick Rajan, Durairaj; Mohan, Kannan; Rajarajeswaran, Jayakumar; Divya, Dharmaraj; Kumar, Ragavendhar; Kandasamy, Sabariswaran; Zhang, Shubing; Ramu Ganesan, Abirami
The marine food-processing industries were producing large quantities of shell wastesas a discard. Currently, this waste material was underutilized and leads to the land-fill as a significant environmental issue. The outer shells or exoskeletons of mollusksserve as the best source of chitin. Three different allomorphs of chitin (γ, β, and γ) wereextracted from different species of crustaceans, mollusks, and fungi. β-Allomorphspredominantly exist in the shells of mollusks. β-Chitin and its deacetylated productchitosan has been utilized for its special characteristic features, including biocom-patibility, environmental friendly, and nontoxic properties. The extraction of β-chitinand chitosan from the mollusk shell waste were evaluated in this work. Hence, thisreview aims to explore edible mollusk shell waste sources and its suitable extractiontechniques, characterizations, and functional properties of mollusk-based β-chitin andchitosan. Further, the genetic pathway of synthesizing mollusk chitin was discussed.The entire life cycle assessment with techno-economic aspects were extrapolated tostudy the bottlenecks and tangible solution for the industrial upscaling of obtainingβ-chitin and chitosan from the edible mollusk shell waste have been reviewed herein.