e) 2020-Scopus Open Access (PDF)

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Author: search.filters.author.Subramanian, Chitra

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    SYNTHESIS, CHARACTERIZATION, THERMAL, THEORETICAL AND ANTIMICROBIAL STUDIES OF SCHIFF BASE LIGAND AND ITS CO(II) AND CU(II) COMPLEXES (Article)
    (Serbian Chemical Society, 2020) Palaniswamy, Radha Venkittapuram; Dhandapani, Mahalakshmi; Suyambulingam, Jonekirubavathy; Subramanian, Chitra
    A Schiff base ligand L was synthesized by condensation of 1,2-diaminoethane with creatinine. The reaction of the ligand with metal chloride salt gives Co(II) and Cu(II) complexes. The synthesized ligand and its metal complexes were characterized by elemental analysis, FT-IR, NMR, UV-Vis, conductivity and magnetic susceptibility measurements as well as thermal analyses. Based on spectral data, tetrahedral geometries have been proposed for the Co(II) and Cu(II) complexes. The molar conductivity data show that the complexes are non-electrolytic in nature. In DFT studies, the geometry of the Schiff base ligand and its Co(II) and Cu(II) complexes were fully optimized using the B3LYP functional together with 6-31g(d,p) and LANL2DZ basis sets. The ligand and its metal complexes were tested against four bacterial species and two fungal species. The results revealed that the metal complexes are more potent against the microbes than the parent ligand.
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    SYNTHESIS, CHARACTERIZATION, BIOLOGICAL AND PHOTOLUMINESCENCE STUDY OF CO(II) COMPLEXES OF FUSED HETEROCYCLIC RING SYSTEMS (Article)
    (Indian Journal of Pharmaceutical Education and Research, 2020-08) Suyambulingam, Jone Kirubavathy; Subramanian, Chitra
    To synthesize and characterize the transition metal complexes of fused heteroccylic ring systems. Background: Many of the fused ring heterocyclic compounds were found to be biologically active in the literature like anti-microbial, anti-cancer, anti-inflammatory, anti-oxidant and so on. The present work focus on the synthesis of the biologically active compounds. Materials and Methods: Synthesis of the ligands and the complexes are done using the standard procedures in earlier reports. Melting points were found using open glass capillaries on a Raaga melting point apparatus and are uncorrected. The percentage of C, H, N , infra-red and UV-Visible spectra of the compounds were recorded using Elementar Vario EL III CHN analyser, Shimadzu spectrophotometer (4000-400 cm-1) and Elico SL 159 UV-Vis spectrophotometer respectively. The antimicrobial activity of the compounds was carried out by well diffusion method. The anticancer activity of the compounds were carried out for the MCF-7 cell line (breast Cancer) using MTT assay. Discussion and Conclusion: Structural elucidation of newly synthesized Co(II) metal complexes of fused heterocyclic ring systems were done using various spectral techniques like FT-IR, 1H-NMR, Electronic and TGA-DTA studies. The anti-microbial activity of the prepared complexes and the DNA Cleavage studies were screened for various test pathogens and explained. The photoluminescence property of the fused heterocyclic ligand and their complexes were studied and compared. Fluorescence enhancement is observed in these complexes which is contradictory to the normal Fluorescence quenching phenomena by added organic derivatives, paved way for photochemical applications.
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    UTILIZATION OF BIOWASTE AS AN ECO-FRIENDLY BIODEGRADABLE CORROSION INHIBITOR FOR MILD STEEL IN 1 MOL/L HCL SOLUTION (Article)
    (Elsevier, 2020-12) Venkatesan, Hemapriya; Mayakrishnan, Prabakaran; Subramanian, Chitra; Manoharan, Swathika; Seung-Hyun, Kim; Ill-Min, Chung
    This report focuses on the application of a biodegradable biowaste [human hair-(HHR)], to produce a mild steel corrosion inhibitor. The performance of HHR extract in inhibiting metallic corrosion in 1 mol/L HCl was investigated. The analysis of the metal corrosion behavior using electrochemical and weight loss techniques revealed that HHR exhibits an efficient corrosion-mitigating effect via adsorption on the metal surface following a Langmuir isotherm. Tafel-plot results revealed the mixed-mode corrosion protection behavior of HHR. Surface analysis using scanning electron microscopy (SEM), energy-dispersive X-ray spectroscopy (EDX), atomic force microscopy (AFM), and Fourier transform infrared (FT-IR) spectroscopy provided evidence for the precipitation of a protective HHR film on the metal surface.