SYNTHESIS OF NOVEL SPIROPYRIMIDINONES

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Date

2010-03-11

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Wiley

Abstract

An efficient one-pot synthesis of new spirocyclic 2-aminopyrimidinones via the three-component reaction of a cyclic ketone, alkyl cyanoacetate, and guanidinium carbonate was developed via a domino reaction

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Keywords

Spiropyrimidinones, one-pot synthesis, anti-microbial activity

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