Department of Botany
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Item PLANT DERIVED EXOSOME- LIKE NANOVESICLES: AN UPDATED OVERVIEW(Elsevier B.V, 2023-02) Subha D; Harshnii K; Madhikiruba K.G; Nandhini M; Tamilselvi K.SExosomes are nanovesicles in the size range of 30–150 nm, produced by mammalian and plant cells. They have the lipid bilayer enclosing a unique mix of biologically active components including proteins, nucleic acids, metabolites and lipids, that depend on their source of origin. The plant derived nanovesicles are gaining considerable research attention due to their ability to be absorbed from the dietary sources. Their bioactive components impart many therapeutic properties to them such as anti-tumorigenic, anti-oxidative, anti-inflammatory, hepatoprotective effects and tissue regeneration. The possibilities of using plant derived exosomes for drug delivery is also promising. This review focusses on the biogenesis and biological nature of exosomes derived from plants and describes their various inherent therapeutic properties. It sheds light on the recently developed methods to study them. The existing challenges in the exosomal research as well as the future prospective are highlighted. Overall, it is an update on the advancements on the research in plant exosomes which can provide a replacement for toxic synthetic drugs and possibilities for disease therapy.Item PLANT DERIVED EXOSOME- LIKE NANOVESICLES: AN UPDATED OVERVIEW(Elsevier, 2023-02) Subha D; Harshnii K; Madhikiruba K G; Nandhini M; Tamilselvi K SExosomes are nanovesicles in the size range of 30–150 nm, produced by mammalian and plant cells. They have the lipid bilayer enclosing a unique mix of biologically active components including proteins, nucleic acids, metabolites and lipids, that depend on their source of origin. The plant derived nanovesicles are gaining considerable research attention due to their ability to be absorbed from the dietary sources. Their bioactive components impart many therapeutic properties to them such as anti-tumorigenic, anti-oxidative, anti-inflammatory, hepatoprotective effects and tissue regeneration. The possibilities of using plant derived exosomes for drug delivery is also promising. This review focusses on the biogenesis and biological nature of exosomes derived from plants and describes their various inherent therapeutic properties. It sheds light on the recently developed methods to study them. The existing challenges in the exosomal research as well as the future prospective are highlighted. Overall, it is an update on the advancements on the research in plant exosomes which can provide a replacement for toxic synthetic drugs and possibilities for disease therapy.Item LEUCAS ASPERA – A REVIEW OF ITS BIOLOGICAL ACTIVITY(Systematic Review in Pharmacy, 2018-01-08) Agnes Nirmala K; Kanchana MHerbal plants are natural source of phytochemicals and widely used in Pharmacetical, food and cosmetic industries. Leucas aspera Linn., commonly known as Thumbai or Dronpushpi is a small erect, branched annual aromatic herb , distributed throughout India from the Himalayas down to Ceylon. Medicinally, it has been proven to possess various pharmacological values like antifungal, antipyretic, antioxidant, antimicrobial, antinociceptive, analgesic, anti-diarrheal, insecticidal, antiinflammatory, analgesic and cytotoxic activity. The Study on various biological properties of this plant will be useful for its potential use in respective industries. The available reports on anti microbial activity, anti oxidant activity and pharmacological value of L. aspera is explained in this review.