Department of Botany
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Item ANTIBACTERIAL EFFECT OF BULBOPHYLLUM NEILGHERRENSE WT. (ORCHIDACEAE). AN INVITRO STUDY(Ancient Science of Life, 2005-12) Priya K; Krishnaveni CThe antibacterial activity of Bulbophyllum neilgherrense was tested against five species of bacteria, viz., Escherichia coli, Staphylococcus aureus, Bacillus pumilus, Pseudomonas aeruginosa and Pseudomonas putida Aqueous, ethanolic and chloroform soluble extracts of leaf and pseudobulb (5.50 w/v) were screened for their antibacterial potential. The zone of inhibition was seen to be largest when alcoholic extract was used.Item EFFECT OF INDIGENOUS DRUGS ON GLUCURONOGLYCAN METABOLISM IN DIABETIC HYPERTENSIVE RABBITS(Pub Med, 1993) Kumari K S; Devi K SDevelopment of hypertension further exaggerated the deranged level of total glucuronoglycan (GAG), different fractions of GAG, activities of synthetic and degradative enzymes of GAG and biological sulphation observed in diabetic rabbits. Administration of indigenous drug preparations (nisakathakathi Kashayam and rasnairandadi Kashayam and its mixture) ameliorated the diabetic hypertensive condition by reversing these effects and thereby arrested.Item INVESTIGATIONS ON MARINE ACTINOMYCETES FROM BAY OF BENGAL NEAR GANGAVARAM COAST OF ANDHRA PRADESH.(Association of Pharmaceutical Innovators, 2009) Kumari K S; Umadevi K; Apparao AllamBay of Bengal Ocean near Gangavaram coast of Andhra Pradesh, India was investigated as a source of actinomycetes to screen for the production of novel bioactive compounds. During our investigation on marine actinomycetes from 6 different marine samples, a total of 51 actinomycetes with distinct characteristics were isolated by plating on starch casein agar medium. The antimicrobial and enzymatic activities were studied for all the isolates. The preliminary study for antimicrobial activity by cross streak method indicated that 21 isolates (41.1%) have excellent antagonistic properties. All these 21 isolates were subjected to detailed submerged fermentation studies. It was observed that 12 isolates (23.5%) exhibited antibacterial activity, 9 isolates (17.6%) showed antifungal activity while 3 isolates (5.8%) showed both antibacterial and antifungal activities. All the isolates were also subjected for the determination of enzymatic activities. 41 isolates (80.3%) exhibited amylolytic activity while 48 isolates (94.1%) showed proteolytic activity.Item IN VITRO REGENERATION OF PHOLIDOTA PALLIDA LINDL. (ORCHIDACEAE)(Indian Journals.com, 2019-07-16) Gladies E Sharone; Krishnaveni T; Devi Chithra B SOrchids exhibit a wide range of diversity in forms, size, colour and texture of flowers beyond the imagination of human mind. Orchids grow in nature through seeds but in the absence of appropriate hosts, they do not germinate in adequate number. This obstacle was overcome by adapting tissue culture technique for appropriate germination of orchids. In vitro techniques have been successfully carried out for the mass propagation of orchid plantlets. Hence, a preliminary study was carried out to develop a suitable protocol for mass multiplication of Pholidota pallida. MS (Murashige and Skoog) medium was found to be suitable for the asymbiotic seed germination of Pholidota pallida. MS medium supplemented with IAA (Indole-3-acetic acid), IBA (Indole-3butyric acid), BAP (6-Benzylaminopurine) and KIN (Kinetin) individually and in combinations induced direct protocorm like bodies. Hormone-free MS basal medium was found suitable for the conversion of PLBs (protocorm-like bodies) into complete plantletsItem PHYTOCHEMICAL AND ANTIMICROBIAL EVALUATION OF THE LEAVES OF ANTIARIS TOXICARIA, (LESCH)(Semantic Scholar, 2016) Kemila P; Krishnaveni CAntiaris toxicaria Lesch. commonly known as bark cloth tree. Its medicinal value is yet unexplored, hence this study forms a basis for the active components present in it and further isolation of the compound. The preliminary phytochemical screening in different solvent extracts of Antiaris toxicaria leaves, collected in the area Anaikatti, Coimbatore District exhibited variations in the presence of phytocompounds depends upon the polarity of solvents, the methanolic extract showed the presence of all phytoconstituents except alkaloids. In the present study, the methanol extract showed good antibacterial activity than chloroform and water extracts. It revealed that the methanol was the most effective solvent for the antibacterial activity. In antifungal activity, the aqueous and methanol extract showed good activity against Cuvularia lunata and Aspergillus flavus in which the zone of inhibition was higher against Aspergillus flavus.Item SURVEY OF ETHNO MEDICINAL PLANTS, NILGIRI BIOSPHERE NATURE PARK AT THUVAIPATHY, ANAIKATTI, COIMBATORE, TAMILNADU, INDIA(Plant Archives, 2019) Hemila P; Krishnaveni CAn ethno medicinal Survey was conducted to collect information about medicinal plants used by Thuvaipathy tribal village people located in the forest area. About 180 medicinal plants are used in various health problems; Majority of the plant parts are stem, bark and leaves. The most representative families were Caesalpinaceae and Moraceae with 13 species each, Euphorbiaceae, and Mimosaceae with 9 species, Sapindaceae and Bignnoniaceae with 8 species each and Annonaceae and Apocynaceae with 6 species. The other families had 5 and below 5 species each associated with the treatment of the reports. The plants were found to be used in different forms such as juice, extracts, paste, powder, infusion. These ethno medicinal plants were used to treat ailments like cold, cough, headache, stomachache, dysentery, skin disease, poison bites, cut and wounds and diabetes.Item ANTIPYRETIC POTENTIAL OF AQUEOUS LEAF EXTRACT OF ANNONA MURICATA.L AND SPERMACOCE ARTICULARIS. L.F. ON YEAST-INDUCED PYREXIA IN RATS(Innovare Academic Sciences Pvt Ltd, 2018) Maruvoor Arasi K; Krishnaveni C: The objective of this study is to evaluate the potential of in vivo antipyretic activity of the aqueous leaf extracts of Annona muricata L. and Spermacoce articularis. L.f.The acute oral toxicity was determined by the Organization of Economic and Cooperation Development-423 class methods, and the in vivo antipyretic activity was determined by brewer’s yeast induced pyrexia method The results showed that the aqueous leaf extract of A. muricata. L and S. articularis L.f plants is non-toxic and possessed significant antipyretic effect This study provides evidence for the antipyretic activity of A. muricata. L and S. articularis L.f. The aqueous leaf extract of S. articularis L.f at a dose of 400 mg/kg showed a more significant effect (p<0.01) in lowering the hypothermia than the extract of A. muricata L but found to have a similar effect as the standard drug aspirin (100 mg/kg)Item QUANTITATIVE PHYTOCHEMICAL ANALYSIS OF ECBOLIUMVIRIDE (FORSK) MERRILL. AND JUSTICIA GENDARUSSABURM. F.(International Journal of Current Trend Research, 2013) S, Subhashini; T V, Poonguzhali; V, Madha sureshIn ethnomedicinal practices, the traditional healers use Ecbolium viride and Justicia gendarussa in the treatment of various ailments. Scientific parameters are used to identify the true plant material and to ensure its quality. Therefore, the present work has been undertaken to establish preliminary quantitative phytochemical profile. The powder of the two plants have shown the presence of tannins, alkaloids, terpenoids, protein, flavonoids, saponins anthraquinones, carbohydrates, glycosides, phenols, steroids, are predominantly present which terpenoids, tannin and flavonoids are of medicinal importance.Item STUDIES ON IN VITRO ANTIBACTERIAL AND ANTIFUNGAL PROPERTY OF ECBOLIUM VIRIDE (FORSK) MERRILL(International Journal of Current Science, 2012) S, Subhashini; T V, PoonguzhaliEcbolium viride an indigenous plant of Eastern India, its known for anti-inflammatory and anti-helmintic property. It was analyzed for its antimicrobial property. The antibacterial property of methanol, ethyl acetate and chloroform of E. viride was studied against different bacteria include Bacillus subtilis, Escherichia coli, Salmonella typhi, and Micrococcus luteus. The antifungal property of methanol, ethyl acetate and chloroform extracts of Ecbolium viride was studied against different fungus which includes Candida albicans, Candida parapsilosis and Candida tropicalis. The extracts were screened for their antimicrobial activity using in vitro well diffusion method at concentrations ranging of 250-1000 μg/mL. Inhibitory zones were pronounced in methanol. Maximum Inhibitory Concentration (MIC) was tested using broth dilution method at concentrations ranging from 100 to 1000 μg/mL. Significant antibacterial and antifungal activity was observed in methanol extract of E. viride leavesItem GC-MS DETERMINATION OF BIOACTIVE COMPONENTS OF WEDELIA CHINENSIS (OSBECK) MERRILL (PDF)(Journal of Chemical and Pharmaceutical Research, 2013) Rehana Banu H; Nagarajan NMedicinal plants are sources of important therapeutic aids for alleviating human ailments. The traditional use of medicinal plants leaf extract for diseases is quite common in developing countries like India. In a view to understand the scientific reason behind its medicinal value, an attempt is made in this study, to analyze major bioactive compounds present in the leaf extract from Wedelia chinensis (Osbeck) Merrill (Family Asteraceae) by GC-MS. The major chemical constituents are 2-Tridecanone (CAS) (4.51%), n-(methoxyphenylmethylene) carbamic acid ethyl ester (1.65%), and 9,12,15-Octadecatrienoic acid, methyl ester, (Z,Z,Z) (13.68%). The presence of some of these constituents in the plant extract provides the scientific evidences for the antimicrobial, anti-tumor, and antioxidant properties of the plant. Further study is required to find out the specific phytochemical which isresponsible for its medicinal value.