Department of Botany

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Author: search.filters.author.Kumari K SEnd date: 2009

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    EFFECT OF INDIGENOUS DRUGS ON GLUCURONOGLYCAN METABOLISM IN DIABETIC HYPERTENSIVE RABBITS
    (Pub Med, 1993) Kumari K S; Devi K S
    Development of hypertension further exaggerated the deranged level of total glucuronoglycan (GAG), different fractions of GAG, activities of synthetic and degradative enzymes of GAG and biological sulphation observed in diabetic rabbits. Administration of indigenous drug preparations (nisakathakathi Kashayam and rasnairandadi Kashayam and its mixture) ameliorated the diabetic hypertensive condition by reversing these effects and thereby arrested.
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    INVESTIGATIONS ON MARINE ACTINOMYCETES FROM BAY OF BENGAL NEAR GANGAVARAM COAST OF ANDHRA PRADESH.
    (Association of Pharmaceutical Innovators, 2009) Kumari K S; Umadevi K; Apparao Allam
    Bay of Bengal Ocean near Gangavaram coast of Andhra Pradesh, India was investigated as a source of actinomycetes to screen for the production of novel bioactive compounds. During our investigation on marine actinomycetes from 6 different marine samples, a total of 51 actinomycetes with distinct characteristics were isolated by plating on starch casein agar medium. The antimicrobial and enzymatic activities were studied for all the isolates. The preliminary study for antimicrobial activity by cross streak method indicated that 21 isolates (41.1%) have excellent antagonistic properties. All these 21 isolates were subjected to detailed submerged fermentation studies. It was observed that 12 isolates (23.5%) exhibited antibacterial activity, 9 isolates (17.6%) showed antifungal activity while 3 isolates (5.8%) showed both antibacterial and antifungal activities. All the isolates were also subjected for the determination of enzymatic activities. 41 isolates (80.3%) exhibited amylolytic activity while 48 isolates (94.1%) showed proteolytic activity.