Browsing by Author "Sabariswaran, Kandasamy"

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AG AND AU NANOPARTICLES DECORATED ON SYNTHETIC CLAY FUNCTIONALIZED MULTI-WALLED CARBON NANOTUBE FOR OXYGEN REDUCTION REACTION
(SpringerLink, 2021-06-03) Narayanamoorthy, Bhuvanendran; Sabarinathan, Ravichandran; Sabariswaran, Kandasamy; Huaneng, Su
A novel clay (aminoclay, AC) functionalized multi-walled carbon nanotube (MWCNT) was employed as a novel hybrid supporting material to Ag and Au nanoparticles for the improvement of oxygen reduction reaction (ORR). The size and structure of the catalysts were studied by XRD and electron microscopy analysis, revealing that the average crystallite and particle size was about 3.4 and 2.6 nm for Au and 16.2 and 15.3 nm for Ag nanoparticles, respectively. The ORR performance was probed by employing the voltammetry techniques under static and hydrodynamic conditions. The results show that the electrochemical surface area of Au (57.5 m2/g) and Ag (17.8 m2/g) on AC/MWCNT are larger than that of AC-free catalysts, and the ORR mechanism follows a direct 4-electron transfer pathway. The supported Au and Ag on AC/MWCNT catalysts explicitly showed the enhanced electrocatalytic efficiency and activity on ORR than that of the AC-free MWCNT catalysts. This work demonstrates that developing surface functionalized carbon support using an inorganic silicate layer (clay minerals) as hybrid support for the persistence of active metal catalysts could be a promising strategy for advanced LT-AFCs ORR electrocatalysts.
ANTIBIOFILM ACTIVITY OF BIOSURFACTANT PRODUCED BY A SPONGE-ASSOCIATED MARINE COBETIA SP. JCG-23
(Springer Link, 2023-09-22) Govindarajan, Ganesan; Chandrasekar, Balu; Suganthi, Ganesan; Samuel Raj, Babu Arulmani; Sabariswaran, Kandasamy
Marine symbiotically associated microbes play a vital role and are an excellent source of natural compounds that exert wide biological activities. In this study, we have reported on the identification, characterization, phylogenetic relationship, and anti-biofilm surface-active compound-producing abilities of marine invertebrate sponge-associated Cobetia sp. JCG-23. Among 24 isolates, a total of five strains (JCG2, JCG19, JCG20, JCG22, and JCG23) have active surface molecule producing potential on the emulsification index assay. Interestingly, the potential candidate JCG-23, produces biosurfactants with low surface tension (22 Nm-1) that exert anti-biofilm activity against Pseudomonas aeruginosa PAO1. The isolate was identified as genus Cobetia sp. JCG-23 with 99.1% sequence similarity to Cobetia crustatorum (EU909460) based on 16S rRNA gene sequence analysis. The large-scale production, purification, stability, and characterization of biosurfactant were carried out and its surface activity was determined using the oil drop method. Subsequent spectral analysis such as UV, FT-IR, and GC-MS analysis indicated that the purified biosurfactant was a hydroxyl fatty acid, namely octadecanoic acid (C18H36O2) with a molecular weight of 284 m/z. Furthermore, the effect of antibiofilm activity on the viability of Pseudomonas aeruginosa PAO1 by static ring tube and light and confocal laser scanning microscopy analysis revealed that the octadecanoic acid from Cobetia sp. JCG-23 has strong biofilm dismantle ability against Pseudomonas aeruginosa PAO1. Further characterization of the biosurfactant from the isolate Cobetia sp. JCG-23 can pave the way for developing novel bioactive agents targeting biofilm-forming pathogens on topical and medical devices.
ANTIBIOFILM ACTIVITY OF BIOSURFACTANT PRODUCED BY A SPONGE-ASSOCIATED MARINE COBETIA SP. JCG-23
(Springer Link, 2023-09-22) Govindarajan, Ganesan; Chandrasekar, Balu; Suganthi, Ganesan; Samuel Raj, Babu Arulmani; Sabariswaran, Kandasamy
Marine symbiotically associated microbes play a vital role and are an excellent source of natural compounds that exert wide biological activities. In this study, we have reported on the identification, characterization, phylogenetic relationship, and anti-biofilm surface-active compound-producing abilities of marine invertebrate sponge-associated Cobetia sp. JCG-23. Among 24 isolates, a total of five strains (JCG2, JCG19, JCG20, JCG22, and JCG23) have active surface molecule producing potential on the emulsification index assay. Interestingly, the potential candidate JCG-23, produces biosurfactants with low surface tension (22 Nm-1) that exert anti-biofilm activity against Pseudomonas aeruginosa PAO1. The isolate was identified as genus Cobetia sp. JCG-23 with 99.1% sequence similarity to Cobetia crustatorum (EU909460) based on 16S rRNA gene sequence analysis. The large-scale production, purification, stability, and characterization of biosurfactant were carried out and its surface activity was determined using the oil drop method. Subsequent spectral analysis such as UV, FT-IR, and GC-MS analysis indicated that the purified biosurfactant was a hydroxyl fatty acid, namely octadecanoic acid (C18H36O2) with a molecular weight of 284 m/z. Furthermore, the effect of antibiofilm activity on the viability of Pseudomonas aeruginosa PAO1 by static ring tube and light and confocal laser scanning microscopy analysis revealed that the octadecanoic acid from Cobetia sp. JCG-23 has strong biofilm dismantle ability against Pseudomonas aeruginosa PAO1. Further characterization of the biosurfactant from the isolate Cobetia sp. JCG-23 can pave the way for developing novel bioactive agents targeting biofilm-forming pathogens on topical and medical devices.
ANTIMICROBIAL, ANTIOXIDANT, ANTICANCER, AND ANTITHROMBOTIC, COMPETENCY OF SAPONINS FROM THE ROOT OF DECALEPIS HAMILTONII
(Elsevier, 2023-08-15) Jayaraman, Gitanjali; Duraisamy, Sumathi Dinesh Ram; Kavitha R; Venkatesan, Amalan; Tahani, Awad Alahmadi; Sulaiman Ali, Alharbi; Sabariswaran, Kandasamy; Rajasree, Shanmuganthan; Natesan, Vijayakumar
The goal of this study was to extract saponins from the tuberous root of Decalepis hamiltonii and assess their potential clinical applications, which included antioxidant, antibacterial, antithrombotic, and anticancer properties. Surprisingly, the results of this study revealed that the extracted saponins have excellent antioxidant activities, as demonstrated by 2,2-diphenylpicrylhydrazyl (DPPH), 2,2′-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS), Hydrogen peroxide (H2O2), and Nitric oxide (NO) scavenging assays. Nonetheless, at a concentration of 100 g/mL, crude saponin had excellent antibacterial activity, particularly against gramme positive bacteria (Staphylococcus aureus, Bacillus subtilis, Staphylococcus epidermidis, and Micrococcus luteus), followed by gramme negative bacteria (Escherichia coli, Salmonella typhi, Proteus mirabilis, and Klebsiella pneumonia). Despite this, the crude saponin had no effect on Aspergillus niger and Candida albicans. The crude saponin also possesses outstanding in vitro antithrombotic activity on blood clot. Interestingly, the crude saponins have an outstanding anticancer activity of 89.26%, with an IC50 value of 58.41 μg/mL. Overall, the findings conclude that crude saponin derived from D. hamiltonii tuberous root could be used in pharmaceutical formulations.
ANTIOXIDANT AND ANTICANCER POTENTIAL OF ETHYL ACETATE EXTRACT OF BARK AND FLOWER OF TECOMA STANS (LINN) AND IN SILICO STUDIES ON PHYTOLIGANDS AGAINST BCL 2 AND VEGFR2 FACTORS
(Elsevier, 2023-02-15) Mathiyazhagan, Narayanan; Anburaj, Gothandapani; Rajasudha, Venugopalan; Manikandan, Rethinam; Sakunthala, Pitchai; Tahani, Awad Alahmadi; Hesham S, Almoallim; Sabariswaran, Kandasamy; Kathirvel, Brindhadevi
This study was designed to appraise the antioxidant and anticancer competence of solvent extracts of Tecoma stans (Linn) and analyze the phytoligands interaction against Bcl 2 VEGFR2 through in silico studies. The phytochemical analysis revealed that the ethyl acetate extract contains more number of pharmaceutically valuable phytochemicals than other solvent extracts. Among the various phytochemicals, flavonoid was found as a predominant component, and UV–Vis- spectrophotometer analysis initially confirmed it. Hence, the column chromatogram was performed to purify the flavonoid, and High-performance liquid chromatography (HPLC) was performed. It revealed that the flavonoid enriched fraction by compared with standard flavonoid molecules. About 84.69% and 80.43% of antioxidant activity were found from ethyl acetate extract of bark and flower at the dosage of 80 μg mL−1 with the IC50 value of 47.24 and 43.40 μg mL−1, respectively. In a dose-dependent mode, the ethyl acetate extract of bark and flower showed cytotoxicity against breast cancer cell line MCF 7 (Michigan Cancer Foundation-7) as up to 81.38% and 80.94% of cytotoxicity respectively. Furthermore, the IC50 was found as 208.507 μg mL−1 and 207.38 μg mL−1 for bark and flower extract correspondingly. About 10 medicinal valued flavonoid components were identified from bark (6) and flower (4) ethyl acetate extract through LC-MS analysis. Out of 10 components, the 3,5-O-dicaffeoylquinic acid (ΔG -8.8) and Isorhamnetin-3-O-rutinoside (ΔG -8.3) had the competence to interact with Bcl 2 (B-Cell Lymphoma 2) and VEGFR2 (Vascular Endothelial Growth Factor Receptor 2) respectively with more energy. Hence, these results confirm that the ethyl acetate extract of bark and flower of T. stans has significant medicinal potential and could be used as antioxidant and anticancer agent after some animal performance study.
ASSESSING POLLUTANT SORPTION EFFICIENCY OF MODIFIED AND UNMODIFIED BIOCHAR WITH BACILLUS CEREUS ON CONTAMINATED LAKE WATER: IMPLICATIONS FOR ORYZA SATIVA SEEDLING AND ARTEMIA FRANCISCANA LARVAE VIABILITY
(Springer Link, 2023-10-02) Mathiyazhagan, Narayanan; Ramesh, Subramani; Sabariswaran, Kandasamy
This study evaluated the efficacy of biochar in removing pollutants from a polluted lake. Biochar, both with and without Bacillus cereus, was assessed for its sorption potential. The treated water samples were analyzed for toxicity using Oryza sativa and Artemia franciscana larvae. The lake water exceeded permissible limits for pH, turbidity, dissolved oxygen (DO), chemical oxygen demand (COD), biological oxygen demand (BOD), and various metals. The 10-day biosorption study with different treatment groups (MB, UMB, MBB, UMBB, and BC) revealed that the MBB group exhibited remarkable pollutant sorption potential. It achieved pollutant removal percentages of 33.35% for Cd, 15.73% for As, 26.21% for Cr, 32.72% for Pb, 32.81% for Zn, 23.58% for Cu, 5.44% for Cl, 22.01% for Ni, 28.2% for Hg, and 4.19% for SO42−. MBB-treated lake water showed no toxicity, confirming pollutant removal by metal-tolerant Bacillus cereus in modified biochar.
ASSESSING POLLUTANT SORPTION EFFICIENCY OF MODIFIED AND UNMODIFIED BIOCHAR WITH BACILLUS CEREUS ON CONTAMINATED LAKE WATER: IMPLICATIONS FOR ORYZA SATIVA SEEDLING AND ARTEMIA FRANCISCANA LARVAE VIABILITY
(Springer Link, 2023-10-02) Mathiyazhagan, Narayanan; Ramesh, Subramani; Sabariswaran, Kandasamy
This study evaluated the efficacy of biochar in removing pollutants from a polluted lake. Biochar, both with and without Bacillus cereus, was assessed for its sorption potential. The treated water samples were analyzed for toxicity using Oryza sativa and Artemia franciscana larvae. The lake water exceeded permissible limits for pH, turbidity, dissolved oxygen (DO), chemical oxygen demand (COD), biological oxygen demand (BOD), and various metals. The 10-day biosorption study with different treatment groups (MB, UMB, MBB, UMBB, and BC) revealed that the MBB group exhibited remarkable pollutant sorption potential. It achieved pollutant removal percentages of 33.35% for Cd, 15.73% for As, 26.21% for Cr, 32.72% for Pb, 32.81% for Zn, 23.58% for Cu, 5.44% for Cl, 22.01% for Ni, 28.2% for Hg, and 4.19% for SO42−. MBB-treated lake water showed no toxicity, confirming pollutant removal by metal-tolerant Bacillus cereus in modified biochar.
ASSESSING POLLUTANT SORPTION EFFICIENCY OF MODIFIED AND UNMODIFIED BIOCHAR WITH BACILLUS CEREUS ON CONTAMINATED LAKE WATER: IMPLICATIONS FOR ORYZA SATIVA SEEDLING AND ARTEMIA FRANCISCANA LARVAE VIABILITY
(Springer Link, 2023-10-02) Mathiyazhagan, Narayanan; Ramesh, Subramani; Sabariswaran, Kandasamy
This study evaluated the efficacy of biochar in removing pollutants from a polluted lake. Biochar, both with and without Bacillus cereus, was assessed for its sorption potential. The treated water samples were analyzed for toxicity using Oryza sativa and Artemia franciscana larvae. The lake water exceeded permissible limits for pH, turbidity, dissolved oxygen (DO), chemical oxygen demand (COD), biological oxygen demand (BOD), and various metals. The 10-day biosorption study with different treatment groups (MB, UMB, MBB, UMBB, and BC) revealed that the MBB group exhibited remarkable pollutant sorption potential. It achieved pollutant removal percentages of 33.35% for Cd, 15.73% for As, 26.21% for Cr, 32.72% for Pb, 32.81% for Zn, 23.58% for Cu, 5.44% for Cl, 22.01% for Ni, 28.2% for Hg, and 4.19% for SO42−. MBB-treated lake water showed no toxicity, confirming pollutant removal by metal-tolerant Bacillus cereus in modified biochar.
ASSESSING THE ECOLOGICAL IMPACT OF PESTICIDES/HERBICIDES ON ALGAL COMMUNITIES: A COMPREHENSIVE REVIEW
(Elsevier B.V, 2024-03) Mathiyazhagan, Narayanan; Kesavan, Devarayan; Monu, Verma; Manickam, Selvaraj; Hamed A, Ghramh; Sabariswaran, Kandasamy
The escalating use of pesticides in agriculture for enhanced crop productivity threatens aquatic ecosystems, jeopardizing environmental integrity and human well-being. Pesticides infiltrate water bodies through runoff, chemical spills, and leachate, adversely affecting algae, vital primary producers in marine ecosystems. The repercussions cascade through higher trophic levels, underscoring the need for a comprehensive understanding of the interplay between pesticides, algae, and the broader ecosystem. Algae, susceptible to pesticides via spillage, runoff, and drift, experience disruptions in community structure and function, with certain species metabolizing and bioaccumulating these contaminants. The toxicological mechanisms vary based on the specific pesticide and algal species involved, particularly evident in herbicides' interference with photosynthetic activity in algae. Despite advancements, gaps persist in comprehending the precise toxic effects and mechanisms affecting algae and non-target species. This review consolidates information on the exposure and toxicity of diverse pesticides and herbicides to aquatic algae, elucidating underlying mechanisms. An emphasis is placed on the complex interactions between pesticides/herbicides, nutrient content, and their toxic effects on algae and microbial species. The variability in the harmful impact of a single pesticide across different algae species underscores the necessity for further research. A holistic approach considering these interactions is imperative to enhance predictions of pesticide effects in marine ecosystems. Continued research in this realm is crucial for a nuanced understanding of the repercussions of pesticides and herbicides on aquatic ecosystems, mainly algae.
ASSESSING THE ECOLOGICAL IMPACT OF PESTICIDES/HERBICIDES ON ALGAL COMMUNITIES: A COMPREHENSIVE REVIEW (Review)
(Elsevier, 2024-03) Mathiyazhagan, Narayanan; Kesavan, Devarayan; Monu, Verma; Manickam, Selvaraj; Hamed A, Ghramh; Sabariswaran, Kandasamy
The escalating use of pesticides in agriculture for enhanced crop productivity threatens aquatic ecosystems, jeopardizing environmental integrity and human well-being. Pesticides infiltrate water bodies through runoff, chemical spills, and leachate, adversely affecting algae, vital primary producers in marine ecosystems. The repercussions cascade through higher trophic levels, underscoring the need for a comprehensive understanding of the interplay between pesticides, algae, and the broader ecosystem. Algae, susceptible to pesticides via spillage, runoff, and drift, experience disruptions in community structure and function, with certain species metabolizing and bioaccumulating these contaminants. The toxicological mechanisms vary based on the specific pesticide and algal species involved, particularly evident in herbicides' interference with photosynthetic activity in algae. Despite advancements, gaps persist in comprehending the precise toxic effects and mechanisms affecting algae and non-target species. This review consolidates information on the exposure and toxicity of diverse pesticides and herbicides to aquatic algae, elucidating underlying mechanisms. An emphasis is placed on the complex interactions between pesticides/herbicides, nutrient content, and their toxic effects on algae and microbial species. The variability in the harmful impact of a single pesticide across different algae species underscores the necessity for further research. A holistic approach considering these interactions is imperative to enhance predictions of pesticide effects in marine ecosystems. Continued research in this realm is crucial for a nuanced understanding of the repercussions of pesticides and herbicides on aquatic ecosystems, mainly algae.
AN ASSESSMENT OF METAL ABSORPTION COMPETENCE OF INDIGENOUS METAL TOLERANT BACTERIAL SPECIES- AN IN-VITRO STUDY
(Elsevier, 2024) Anusha, P; Natarajan, D; Sumathy, Rengarajan; Saleh, Alfarraj; Sabariswaran, Kandasamy
Heavy metals pose a serious global threat to the environment. Hence, removing hazardous metals from soil samples has become complicated over the past few years. The current work looked into the remediation of heavy metals from aqueous solutions using a bacterial community and a unique bacterium obtained from metal-contaminated soil. In this investigation, the isolates of Bacillus anthracis A1-7, Bacillus. thuringiensis A1-3, Bacillus. cereus A1-5, and Pseudomonas aeruginosa A-33 actively demonstrated metal tolerances to various tested metals. Furthermore, an in-vitro biosorption study was performed under ideal concentration. The bacterial consortia achieved the highest biosorption effectiveness for Cu & Zn, 92.7% and 90.3%, respectively. When compared with a single bacterium, the group exhibited inferior Pb biosorption (86%). Since then, P. aeruginosa A33 has had the highest Pb biosorption. Finally, a bacterial consortium has devised an intriguing strategy for eliminating Cu and Pb from the polluted medium. P. aeruginosa A33 was found to be a mighty microbe that extracts Zn from polluted water. This metal-tolerant bacterium also exhibited specific proportions of selective commercially available antibiotics, which were analyzed using the Multiple Antibiotic Resistance (MAR) Index. In conclusion, these findings indicated that bacterial consortia composed of four bacterial isolates can remove metals from a metal-polluted medium.
AN ASSESSMENT OF METAL ABSORPTION COMPETENCE OF INDIGENOUS METAL TOLERANT BACTERIAL SPECIES- AN IN-VITRO STUDY
(Elsevier Inc, 2024-06) Anusha, P; Natarajan, D; Sumathy, Rengarajan; Saleh, Alfarraj; Sabariswaran, Kandasamy
Heavy metals pose a serious global threat to the environment. Hence, removing hazardous metals from soil samples has become complicated over the past few years. The current work looked into the remediation of heavy metals from aqueous solutions using a bacterial community and a unique bacterium obtained from metal-contaminated soil. In this investigation, the isolates of Bacillus anthracis A1-7, Bacillus. thuringiensis A1-3, Bacillus. cereus A1-5, and Pseudomonas aeruginosa A-33 actively demonstrated metal tolerances to various tested metals. Furthermore, an in-vitro biosorption study was performed under ideal concentration. The bacterial consortia achieved the highest biosorption effectiveness for Cu & Zn, 92.7% and 90.3%, respectively. When compared with a single bacterium, the group exhibited inferior Pb biosorption (86%). Since then, P. aeruginosa A33 has had the highest Pb biosorption. Finally, a bacterial consortium has devised an intriguing strategy for eliminating Cu and Pb from the polluted medium. P. aeruginosa A33 was found to be a mighty microbe that extracts Zn from polluted water. This metal-tolerant bacterium also exhibited specific proportions of selective commercially available antibiotics, which were analyzed using the Multiple Antibiotic Resistance (MAR) Index. In conclusion, these findings indicated that bacterial consortia composed of four bacterial isolates can remove metals from a metal-polluted medium.
ASSESSMENTS OF THE POWER PRODUCTION, ENERGY CONSUMPTION AND EMISSION COMPARISON OF HYDROGEN FEED VEHICLES
(Elsevier, 2023-02) Xiumei, Zhang; Changlei, Xia; Mohamad S, AlSalhi; Sandhanasamy, Devanesan; Manigandan, Sekar; G K, Jhanani; Sabariswaran, Kandasamy; Hui, Li
The use of second-generation biodiesel has been increasing swiftly in the place of petroleum fuels. This paper explains the influence of chicken waste on a direct injection diesel engine performance, combustion and emission characteristics. The combination of hydrogen and biodiesel derived from waste chicken fat were examined across various engine speeds such as 1000 rpm, 1500 rpm, 2000 rpm, 2500 rpm and 3000 rpm. The hydrogen is a green and efficient fuel that was mixed with the biodiesel at the level of 5 liter per minute. The tested biodiesel blends were C0 (Diesel 100%), C15 (Chicken fat biodiesel 15%+pure diesel 85 %), C30 (Chicken fat biodiesel 30%+pure diesel 70%), CH5 (Diesel + 5 LPM Hydrogen), C15H5 (Chicken fat biodiesel 15%+pure diesel 85%+ 5LPM), and CF30H5 (Chicken fat biodiesel 30%+pure diesel 70%+ 5LPM Hydrogen). The results proved that the hydrogen enriched biodiesel improved the performance in terms of brake thermal efficiency, brake power and lowered the brake specific fuel consumption. At higher speeds CH5 produced higher brake power, however at lower speeds C15H5 and C30H5. Further the blend C30H5 reported the maximum BTE of 38% at 2000 rpm. With regard to emissions, all the biodiesel blends reported to produce least carbon monoxide (CO) emission. However, all biodiesel blends reported marginal increase in the nitrogen of oxides (NOx) and carbon dioxide (CO2) irrespective of the engine speeds.
THE BIOTRANSFORMATION POTENTIAL OF BACILLUS CEREUS ON Β- CYPERMETHRIN TO PROTECT THE EARTHWORM (PERIONYX EXCAVATUS) ON INSECTICIDE -CONTAMINATED SOIL
(Taylor & Francis Online, 2022) Mathiyazhagan, Narayanan; Jimmandiyur, Mathappan Murugan; Gajendiran, Kandasamy; Sabariswaran, Kandasamy; Manikandan, Rajendran
The pre-isolated B. cereus had shown better β-cypermethrin resistance at 100 mg L−1 dosage in the Mineral Salt Medium (MSM). Hence, it was applied for the biodegradation study on MSM. The GC-MS analysis revealed that the B. cereus had the potential to degrade β-cypermethrin and metabolize it into six predominant less or nontoxic components (benzene, 1-ethyl−3-methyl-, ethanethiol, 2-(dimethylamino)-, 1-(2-acetoxyethyl)-3,6-diazahomoadamantan-9-one, silane, 9-anthracenyltrimethyl-, 1-(3-hydroxy-3-methylbutyl)-3,6-,fumaric acid). Based on this biodegradation potential, four experimental groups, namely A, B, C, D and control, were framed and the biodegradation potential of B. cereus on β-cypermethrin and interaction with P. excavates were studied. Group C, which includes B. cereus and 10 P. excavates under β-cypermethrin stress excavates positive survival interaction. It was confirmed by the presence of metabolites such as benzene, 1-ethyl-3-methyl-, ethanethiol, 2-(dimethylamino)- and 1-(2-acetoxyethyl)-3,6-diazahomoadamantan-9-one, in P. excavates. Furthermore, these were similar to the metabolites of β-cypermethrin degraded by B. cereus. These results conclude that the biodegradation potential of B. cereus can protect the life of P. excavates from β-cypermethrin toxicity and thus, can support the balancing of soil fertility, structure and soil biotas such as flora and fauna.
CHITOSAN-BASED INSECTICIDE FORMULATIONS FOR INSECT PEST CONTROL MANAGEMENT: A REVIEW OF CURRENT TRENDS AND CHALLENGES
(Elsevier B.V, 2024-09) Kannan, Mohan; Sabariswaran, Kandasamy; Jayakumar, Rajarajeswaran; Thanigaivel, Sundaram; Marko, Bjeljac; Ramya Preethi, Surendran; Abirami Ramu, Ganesan
Future agricultural practices necessitate green alternatives to replace hazardous insecticides while distinguishing between pests and beneficial insects. Chitosan, as a biological macromolecule derived from chitin, is biodegradable and exhibits low toxicity to non-target organisms, making it a sustainable alternative to synthetic pesticides. This review identifies chitosan-derivatives for insecticidal activity and highlights its efficacy including genotoxicity, defense mechanism, and disruption of insect's exoskeleton at different concentrations against several insect pests. Similarly, synergistic effects of chitosan in combination with natural extracts, essential oils, and plant-derived compounds, enhances insecticidal action against various pests was evaluated. The chitosan-based insecticide formulations (CHIF) in the form of emulsions, microcapsules, and nanoparticles showed efficient insecticide action on the targeted pests with less environmental impact. The current challenges associated with the field-trial application were also recognized, by optimizing potent CHIF-formulation parameters, scaling-up process, and regulatory hurdles addressed alongside potential solutions. These findings will provide insight into achieving the EU mission of reducing chemical pesticides by 50 %.
THE COMPREHENSIVE REVIEW ON 3D PRINTING- PHARMACEUTICAL DRUG DELIVERY AND PERSONALIZED FOOD AND NUTRITION
(Elsevier Ltd, 2024-11) Meenakshi, Murugan; Selva Kumar, Ramasamy; Geetha, Venkatesan; Jintae, Lee; Selvaraj, Barathi; Sabariswaran, Kandasamy; Prakash Kumar Sarangi
Three-dimensional printing is one of the emerging technologies that is gaining interest from the pharmaceutical industry as it provides an opportunity to customize drugs according to each patient's needs. Combining different active pharmaceutical ingredients, using different geometries, and providing sustained release enhances the effectiveness of medicine. One of the most innovative uses of 3D printing is producing fabrics, medical devices, medical implants, orthoses, and prostheses. This review summarizes the various 3D printing techniques such as stereolithography, inkjet printing, thermal inkjet printing, fused deposition modelling, extrusion printing, semi-solid extrusion printing, selective laser sintering, and hot-melt extrusion. Also, discusses the drug relies profile and its mechanisms, characteristics, and applications of the most common types of 3D printed API formulations and its recent development. Here, Authors also, summarizes the central flow of 3D food printing process and knowledge extension toward personalized nutrition.
THE COMPREHENSIVE REVIEW ON 3D PRINTING- PHARMACEUTICAL DRUG DELIVERY AND PERSONALIZED FOOD AND NUTRITION
(Elsevier Ltd, 2024) Meenakshi, Murugan; Selva Kumar, Ramasamy; Geetha, Venkatesan; Jintae, Lee; Selvaraj, Barathi; Sabariswaran, Kandasamy; Prakash Kumar, Sarangi
Three-dimensional printing is one of the emerging technologies that is gaining interest from the pharmaceutical industry as it provides an opportunity to customize drugs according to each patient's needs. Combining different active pharmaceutical ingredients, using different geometries, and providing sustained release enhances the effectiveness of medicine. One of the most innovative uses of 3D printing is producing fabrics, medical devices, medical implants, orthoses, and prostheses. This review summarizes the various 3D printing techniques such as stereolithography, inkjet printing, thermal inkjet printing, fused deposition modelling, extrusion printing, semi-solid extrusion printing, selective laser sintering, and hot-melt extrusion. Also, discusses the drug relies profile and its mechanisms, characteristics, and applications of the most common types of 3D printed API formulations and its recent development. Here, Authors also, summarizes the central flow of 3D food printing process and knowledge extension toward personalized nutrition.
CORRIGENDUM TO “FOOD WASTE-DERIVED BLACK SOLDIER FLY (HERMETIA ILLUCENS) LARVAL RESOURCE RECOVERY: A CIRCULAR BIOECONOMY APPROACH” PROCESS SAF. ENVIRON (Erratum)
(Elsevier Ltd, 2024-04) Abirami, Ramu Ganesan; Kannan, Mohan; Sabariswaran, Kandasamy; Ramya, Preethi Surendran; Ragavendhar, Kumar; Durairaj, Karthick Rajan; Jayakumar, Rajarajeswaran
THE CURRENT STATE OF ALGAE IN WASTEWATER TREATMENT AND ENERGY CONVERSION: A CRITICAL REVIEW
(Elsevier, 2023-06) Sabariswaran, Kandasamy; Mathiyazhagan, Narayanan; Rathinam, Raja; Kesavan, Devarayan; R, Kavitha
Due to the rapid expansion of the global economy and population, there aren't enough water resources accessible for direct human consumption. Therefore, water remediation will unavoidably take center stage on a worldwide platform. The development of microalgae can be supported by several types of wastewater (WW). They might be able to clean up pollutants from industry and urban effluents. Due to its low energy requirements, microalgae's capacity to survive in various environmental circumstances, and the potential to convert WW nutrients into high-value chemicals, microalgae-based wastewater treatment (WWT) has already received attention. Recent studies have reported using microalgae to remove pharmaceutical compounds and pesticides from wastewater produced by industrial and agricultural processes and removing nutrients from wastewater from WWTs. As a result, utilizing microalgae for both wastewater treatment and biofuel production could be a cost-effective solution to these challenges. This review emphasizes recent developments in the production of microalgae for WW cleanup. Additionally, it highlights the current problems and opportunities in the emerging algae-based sector.
THE CURRENT STATE OF ALGAE IN WASTEWATER TREATMENT AND ENERGY CONVERSION: A CRITICAL REVIEW
(Elsevier, 2023-06) Sabariswaran, Kandasamy; Mathiyazhagan, Narayanan; Rathinam, Raja; Kesavan, Devarayan; Kavitha, R
Due to the rapid expansion of the global economy and population, there aren't enough water resources accessible for direct human consumption. Therefore, water remediation will unavoidably take center stage on a worldwide platform. The development of microalgae can be supported by several types of wastewater (WW). They might be able to clean up pollutants from industry and urban effluents. Due to its low energy requirements, microalgae's capacity to survive in various environmental circumstances, and the potential to convert WW nutrients into high-value chemicals, microalgae-based wastewater treatment (WWT) has already received attention. Recent studies have reported using microalgae to remove pharmaceutical compounds and pesticides from wastewater produced by industrial and agricultural processes and removing nutrients from wastewater from WWTs. As a result, utilizing microalgae for both wastewater treatment and biofuel production could be a cost-effective solution to these challenges. This review emphasizes recent developments in the production of microalgae for WW cleanup. Additionally, it highlights the current problems and opportunities in the emerging algae-based sector.