Browsing by Author "Kshitij R B, Singh"
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Item CONDUCTING POLYMER-BASED ELECTROCHEMICAL BIOSENSORS FOR BIOMEDICAL APPLICATION(Royal Society of Chemistry, 2023-07-12) Kshitij R B, Singh; Pooja, Singh; Arunadevi, Natarajan; Sushma, Thapa; Ranjana, Verma; Jay, Singh; Ravindra, Pratap SinghMany people are interested in conducting polymers because of their unique qualities, such as biocompatibility, flexibility, low weight, simplicity of production, and capacity for surface modification. They are a top choice for use in biomedical applications, particularly in the highly sensitive and direct diagnostics of coronavirus, diabetes, neurological illnesses, etc. This chapter summarizes the advances in electrochemical sensing based on conducting polymers as active material. At the same time, a significant amount of deep insight into the electrochemical biosensor is provided. Additionally, a thorough investigation is shown on conducting polymers’ use in biomedical applications and their promise for the future.Item MOLECULARLY IMPRINTED POLYMER-BASED OPTICAL IMMUNOSENSORS(Pub Med, 2023-07) Kshitij R B, Singh; Arunadevi, NatarajanMolecularly imprinted polymers (MIPs) are artificial antibodies for a target molecule. The review focuses mainly on mechanistic steps involved in forming MIPs and the role of co-monomers and porogen. In addition, the electronic transition between different energy levels is explained with the help of the Jablonski diagram. Diverse receptor and target molecules for anchoring artificial MIPs are discussed, accentuating the synergetic effects obtained. The binding efficiency, selectivity, and sensitivity of various optical sensors are discussed intensively. In addition to this, we focused on synthesis, physical forms, characterization techniques, and microorganism detection of imprinted polymers. A brief investigation on the use of MIPs in cancer diagnosis is also included, and attention is extended to the important challenges faced in using imprinted polymers.Item MOLECULARLY IMPRINTED POLYMER-BASED OPTICAL IMMUNOSENSORS(Wiley Analytical Science, 2023) Kshitij R B, Singh; Arunadevi, NatarajanMolecularly imprinted polymers (MIPs) are artificial antibodies for a target molecule. The review focuses mainly on mechanistic steps involved in forming MIPs and the role of co-monomers and porogen. In addition, the electronic transition between different energy levels is explained with the help of the Jablonski diagram. Diverse receptor and target molecules for anchoring artificial MIPs are discussed, accentuating the synergetic effects obtained. The binding efficiency, selectivity, and sensitivity of various optical sensors are discussed intensively. In addition to this, we focused on synthesis, physical forms, characterization techniques, and microorganism detection of imprinted polymers. A brief investigation on the use of MIPs in cancer diagnosis is also included, and attention is extended to the important challenges faced in using imprinted polymers.